CAS 125110-14-7|Cefixime trihydrate
| Common Name | Cefixime trihydrate | ||
|---|---|---|---|
| CAS Number | 125110-14-7 | Molecular Weight | 507.495 |
| Density | / | Boiling Point | / |
| Molecular Formula | C16H21N5O10S2 | Melting Point | 218-225℃ |
| MSDS | ChineseUSA | Flash Point | / |
| Symbol | GHS08 | Signal Word | Danger |
Names
| Name | Ytterbium(III) ionophore I,Cefixime trihydrate |
|---|---|
| Synonym | More Synonyms |
Cefixime trihydrate BiologicalActivity
| Description | Cefixime trihydrate (FR-17027 trihydrate) is an antibiotic and a third generation cephalosporin antibiotic, useful for the treatment of a number of bacterial infections[1][2]. |
|---|---|
| Related Catalog | Research Areas >>InfectionResearch Areas >>Inflammation/ImmunologySignaling Pathways >>Anti-infection >>Bacterial |
| References | [1]. Neu HC, et al. In vitro activity of a new broad spectrum, beta-lactamase-stable oral cephalosporin, cefixime. Pediatr Infect Dis J. 1987 Oct;6(10):958-62. [2]. Unemo M, et al. High-level cefixime- and ceftriaxone-resistant Neisseria gonorrhoeae in France: novel penA mosaic allele in a successful international clone causes treatment failure. Antimicrob Agents Chemother. 2012 Mar;56(3):1273-80. |
Chemical & Physical Properties
| Melting Point | 218-225℃ |
|---|---|
| Molecular Formula | C16H21N5O10S2 |
| Molecular Weight | 507.495 |
| Exact Mass | 507.072968 |
| PSA | 265.74000 |
| LogP | 0.17230 |
| InChIKey | HPRLWADTNARROR-JUZDKLSSSA-N |
| SMILES | C=CC1=C(C(=O)O)N2C(=O)C(NC(=O)C(=NOCC(=O)O)c3csc(N)n3)C2SC1.O |
Safety Information
| Symbol | GHS08 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H317-H334 |
| Precautionary Statements | P261-P280-P342 + P311 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Faceshields;Gloves |
| Hazard Codes | Xn |
| Risk Phrases | R42/43 |
| Safety Phrases | S22 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
Articles6
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| Characterization of urinary tract infection-associated Shiga toxin-producing Escherichia coli. Infect. Immun. 82(11) , 4631-42, (2014) Enterohemorrhagic Escherichia coli (EHEC), a subgroup of Shiga toxin (Stx)-producing E. coli (STEC), is a leading cause of diarrhea and hemolytic-uremic syndrome (HUS) in humans. However, urinary trac... | |
| The characterization and antibiotic resistance profiles of clinical Escherichia coli O25b-B2-ST131 isolates in Kuwait. BMC Microbiol. 14 , 214, (2014) Escherichia coli O25b-B2-ST131 are considered virulent extra-intestinal pathogens causing serious clinical complications such as urinary tract infection and bacteraemia. Our main objectives in this st... |
Synonyms
| (6R,7R)-7-({(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetyl}amino)-8-oxo-3-vinyl-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid trihydrate |
| CEFIXIME TRIHYDRATE |
| 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-[(carboxymethoxy)imino]-1-oxoethyl]amino]-3-ethenyl-8-oxo-, (6R,7R)-, hydrate (1:3) |
