CAS 753-90-2|trifluoroethylamine

Introduction：Basic information about CAS 753-90-2|trifluoroethylamine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Customs
6. Articles3
7. Synonyms

Common Name	trifluoroethylamine
CAS Number	753-90-2	Molecular Weight	99.055
Density	1.2±0.1 g/cm3	Boiling Point	36.0±35.0 °C at 760 mmHg
Molecular Formula	C₂H₄F₃N	Melting Point	37-38ºC
MSDS	ChineseUSA	Flash Point	-16.7±0.0 °C
Symbol	GHS02, GHS05, GHS07	Signal Word	Danger

Names

Name	2,2,2-Trifluoroethylamine
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.2±0.1 g/cm3
Boiling Point	36.0±35.0 °C at 760 mmHg
Melting Point	37-38ºC
Molecular Formula	C₂H₄F₃N
Molecular Weight	99.055
Flash Point	-16.7±0.0 °C
Exact Mass	99.029587
PSA	26.02000
LogP	0.24
Vapour Pressure	501.5±0.1 mmHg at 25°C
Index of Refraction	1.301
Storage condition	2-8°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KS0175000

CHEMICAL NAME :: Ethylamine, 2,2,2-trifluoro-

CAS REGISTRY NUMBER :: 753-90-2

BEILSTEIN REFERENCE NO. :: 1733204

LAST UPDATED :: 199701

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C2-H4-F3-N

MOLECULAR WEIGHT :: 99.07

WISWESSER LINE NOTATION :: Z1XFFF

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 4170 mg/m3/2H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,606,1986

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >250 uL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 2,184,1950 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1 gm/m3/17W-I

TOXIC EFFECTS :: Brain and Coverings - recordings from specific areas of CNS Kidney, Ureter, Bladder - proteinuria Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 14(11),59,1970

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 1 gm/m3/17W-I

TOXIC EFFECTS :: Brain and Coverings - recordings from specific areas of CNS Kidney, Ureter, Bladder - proteinuria Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 14(11),59,1970 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83055 No. of Facilities: 10 (estimated) No. of Industries: 1 No. of Occupations: 22 No. of Employees: 1421 (estimated)

Safety Information

Symbol	GHS02, GHS05, GHS07
Signal Word	Danger
Hazard Statements	H225-H302-H314
Precautionary Statements	P210-P280-P305 + P351 + P338-P310
Personal Protective Equipment	Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US)
Hazard Codes	F:Flammable;C:Corrosive;
Risk Phrases	R11;R34
Safety Phrases	S26-S36/37/39-S45
RIDADR	UN 2733 3/PG 2
WGK Germany	3
RTECS	KS0175000
Packaging Group	II
Hazard Class	3
HS Code	2921199090

Customs

HS Code	2921199090
Summary	2921199090 other acyclic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles3

The many roles for fluorine in medicinal chemistry.

J. Med. Chem. 51 , 4359-69, (2008)

Corona discharge ion mobility spectrometry with orthogonal acceleration time of flight mass spectrometry for monitoring of volatile organic compounds.

Anal. Chem. 84(12) , 5327-34, (2012)

We demonstrate the application of corona discharge ion mobility spectrometry with orthogonal acceleration time of flight mass spectrometry (CD IMS-oaTOF) for volatile organic compounds (VOCs) monitori...

Headspace sampling with in situ carbodiimide-mediated derivatization for the determination of ibuprofen in water samples.

J. Chromatogr. A. 1218(30) , 4856-62, (2011)

A method using headspace generation and in situ derivatization with water soluble EDC (1-[3-(dimethylamino)propyl]-3-ethylcarbodiimide) and TFEA (2,2,2-trifluoroethylamine) has been optimized for the ...

Synonyms

Ethanamine, 2,2,2-trifluoro-

trifluoroethylamine

2,2,2-Trifluoroethanamine

EINECS 212-041-3

MFCD00008132

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