CAS 855-96-9|Eupatorin
| Common Name | Eupatorin | ||
|---|---|---|---|
| CAS Number | 855-96-9 | Molecular Weight | 344.315 |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 587.0±50.0 °C at 760 mmHg |
| Molecular Formula | C18H16O7 | Melting Point | 194-196°C |
| MSDS | ChineseUSA | Flash Point | 216.0±23.6 °C |
| Symbol | GHS06 | Signal Word | Danger |
Names
| Name | 5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-6,7-dimethoxy-4H-chromen-4-one |
|---|---|
| Synonym | More Synonyms |
Eupatorin BiologicalActivity
| Description | Eupatorin, a naturally occurring flavone, arrests cells at the G2-M phase of the cell cycle and induces apoptotic cell death involving activation of multiple caspases, mitochondrial release of cytochrome c and poly(ADP-ribose) polymerase cleavage[1]. |
|---|---|
| Related Catalog | Research Areas >>CancerSignaling Pathways >>Others >>Others |
| References | [1]. Estévez S, et al. Eupatorin-induced cell death in human leukemia cells is dependent on caspases and activates the mitogen-activated protein kinase pathway. PLoS One. 2014 Nov 12;9(11):e112536. |
Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 587.0±50.0 °C at 760 mmHg |
| Melting Point | 194-196°C |
| Molecular Formula | C18H16O7 |
| Molecular Weight | 344.315 |
| Flash Point | 216.0±23.6 °C |
| Exact Mass | 344.089600 |
| PSA | 98.36000 |
| LogP | 2.96 |
| Vapour Pressure | 0.0±1.7 mmHg at 25°C |
| Index of Refraction | 1.627 |
| InChIKey | KLAOKWJLUQKWIF-UHFFFAOYSA-N |
| SMILES | COc1ccc(-c2cc(=O)c3c(O)c(OC)c(OC)cc3o2)cc1O |
| Storage condition | room temp |
Safety Information
| Symbol | GHS06 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H301 |
| Precautionary Statements | P301 + P310 |
| Hazard Codes | T |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36 |
| RIDADR | UN 2811 6.1 / PGIII |
| HS Code | 2932999099 |
Customs
| HS Code | 2932999099 |
|---|---|
| Summary | 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Articles10
More Articles| Analysis of vervain flavonoids by HPLC/Diode array detector method. Its application to quality control. J. Agric. Food Chem. 47(11) , 4579-82, (1999) A reversed-phase HPLC procedure is proposed for the determination of seven flavonoids (luteolin, nepetin, hispidulin, jaceosidin, cirsimaritin, cirsilineol, and eupatorin) in vervain samples. A simple... | |
| Flavones and rosmarinic acid from Salvia limbata. Nat. Prod. Res. 24(20) , 1902-6, (2010) The genus Salvia (Lamiaceae) contains more than 50 shrub species in Iran, and Salvia limbata C.A. Meyer grows widely in the north and central parts of the country. Six flavones and rosmarinic acid wer... | |
| Flavonoids eupatorin and sinensetin present in Orthosiphon stamineus leaves inhibit inflammatory gene expression and STAT1 activation. Planta Med. 78(8) , 779-86, (2012) Cytokines and other inflammatory mediators, such as prostaglandin E₂ (PGE₂) and nitric oxide (NO) produced by cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS), respectively, activat... |
Synonyms
| MFCD00016929 |
| 4H-1-Benzopyran-4-one, 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-6,7-dimethoxy- |
| 5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-6,7-dimethoxy-4H-1-benzopyran-4-one |
| 5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-6,7-dimethoxy-4H-chromen-4-one |
| 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-6,7-dimethoxy-4-chromenone |
| 3',5-dihydroxy-4',6,7-trimethoxyflavone |
| eupatorin |
| 6-methoxyluteolin-4',7-dimethyl ether |
