CAS 126-81-8|Dimedone

Introduction：Basic information about CAS 126-81-8|Dimedone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Dimedone BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
5. Safety Information
6. Customs
7. Articles32
8. Synonyms

Common Name	Dimedone
CAS Number	126-81-8	Molecular Weight	140.18
Density	1.0±0.1 g/cm3	Boiling Point	233.7±23.0 °C at 760 mmHg
Molecular Formula	C₈H₁₂O₂	Melting Point	146-148 °C(lit.)
MSDS	ChineseUSA	Flash Point	85.1±19.6 °C

Names

Name	5,5-Dimethyl-1,3-cyclohexanedione
Synonym	More Synonyms

Dimedone BiologicalActivity

Description	5,5-Dimethylcyclohexane-1,3-dione is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Related Catalog	Research Areas >>OthersSignaling Pathways >>Others >>Others
In Vitro	抗癌、抗氧化、抗组胺和抗凝血剂。

Chemical & Physical Properties

Density	1.0±0.1 g/cm3
Boiling Point	233.7±23.0 °C at 760 mmHg
Melting Point	146-148 °C(lit.)
Molecular Formula	C₈H₁₂O₂
Molecular Weight	140.18
Flash Point	85.1±19.6 °C
Exact Mass	140.083725
PSA	34.14000
LogP	0.15
Vapour Pressure	0.1±0.5 mmHg at 25°C
Index of Refraction	1.453
InChIKey	BADXJIPKFRBFOT-UHFFFAOYSA-N
SMILES	CC1(C)CC(=O)CC(=O)C1
Storage condition	2-8°C
Stability	Stable, but may be light sensitive. Incompatible with strong oxidizing agents.
Water Solubility	0.416 g/100 mL (25 ºC)

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GV0345000

CHEMICAL NAME :: 1,3-Cyclohexanedione, 5,5-dimethyl-

CAS REGISTRY NUMBER :: 126-81-8

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C8-H12-O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC) Volume(issue)/page/year: 5,28,1953

Safety Information

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi
Risk Phrases	R36/37/38
Safety Phrases	S24/25
RIDADR	NONH for all modes of transport
WGK Germany	2
RTECS	GV0345000
HS Code	29142900

Customs

HS Code	2914299000
Summary	2914299000. other cyclanic, cyclenic or cyclotherpenic ketones without other oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

Articles32

[The role of aldehydes in development of oxidative stress under rhabdomyolysis in rats].

Fiziol. Zh. 59(1) , 25-31, (2013)

We investigated the changes in the forms of plasma iron and participation of aldehydes in the development of oxidative stress under glycerol-induced rhabdomyolysis in rats. Rhabdomyolysis was caused b...

Thiol-blocking electrophiles interfere with labeling and detection of protein sulfenic acids.

FEBS J. 280(23) , 6150-61, (2013)

Cellular exposure to reactive oxygen species induces rapid oxidation of DNA, proteins, lipids and other biomolecules. At the proteome level, cysteine thiol oxidation is a prominent post-translational ...

Open season for hunting and trapping post-translational cysteine modifications in proteins and enzymes.

ChemBioChem. 12(6) , 841-4, (2011)

Synonyms

Dimedone

1,1-Dimethyl-3,5-diketocyclohexane

cyclohexane-1,3-dione, 5,5-dimethyl-

1,1-Dimethyl-3,5-cyclohexanedione

Methone

Dimedone,Methone

Dimethyldihydroresorcinol

5,5-Dimethylcyclohexane-1,3-dione

MFCD00001588

1,3-Cyclohexanedione, 5,5-dimethyl-

5,5-Dimethyldihydroresorcinol

5,5-Dimethyl-1,3-cyclohexanedione

EINECS 204-804-4

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