Introduction：Basic information about CAS 536709-33-8|Ezetimibe Hydroxy Glucuronide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Ezetimibe Hydroxy Glucuronide |
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| CAS Number | 536709-33-8 | Molecular Weight | 585.55 |
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| Density | 1.547g/cm3 | Boiling Point | 863.74ºC at 760 mmHg |
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| Molecular Formula | C30H29F2NO9 | Melting Point | 127-129ºC |
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| MSDS | / | Flash Point | 476.173ºC |
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Names
| Name | Ezetimibe Hydroxy β-D-Glucuronide |
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| Synonym | More Synonyms |
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Ezetimibe Hydroxy Glucuronide BiologicalActivity
| Description | Ezetimibe hydroxy glucuronide (SCH 488128) is a trace metabolite detected in dog and human plasma samples after oral administration of Ezetimibe (HY-17376)[1]. |
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| Related Catalog | Research Areas >>Cardiovascular DiseaseSignaling Pathways >>Others >>Others |
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| References | [1]. Anima Ghosal, et al. Identification of human UDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation of ezetimibe (Zetia). Drug Metab Dispos. 2004 Mar;32(3):314-20. [2]. Ghosal A, et al. Identification of human UDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation of ezetimibe (Zetia). Drug Metab Dispos. 2004 Mar;32(3):314-20. |
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Chemical & Physical Properties
| Density | 1.547g/cm3 |
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| Boiling Point | 863.74ºC at 760 mmHg |
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| Melting Point | 127-129ºC |
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| Molecular Formula | C30H29F2NO9 |
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| Molecular Weight | 585.55 |
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| Flash Point | 476.173ºC |
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| Exact Mass | 585.18100 |
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| PSA | 156.99000 |
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| LogP | 2.86980 |
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| Index of Refraction | 1.68 |
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| InChIKey | MPXLJVWGRVISEQ-ADEYADIWSA-N |
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| SMILES | O=C(O)C1OC(OC(CCC2C(=O)N(c3ccc(F)cc3)C2c2ccc(O)cc2)c2ccc(F)cc2)C(O)C(O)C1O |
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Synonyms
| (2S,3S,4S,5R,6R)-6-[(1S)-1-(4-fluorophenyl)-3-[(2S,3R)-1-(4-fluorophenyl)-2-(4-hydroxyphenyl)-4-oxoazetidin-3-yl]propoxy]-3,4,5-trihydroxyoxane-2-carboxylic acid |
