CAS 54-12-6|DL-Tryptophan

Human Endogenous Metabolite

CHEMICAL IDENTIFICATION

RTECS NUMBER :

YN6129200

CHEMICAL NAME :

Tryptophan, DL-

CAS REGISTRY NUMBER :

54-12-6

LAST UPDATED :

199709

DATA ITEMS CITED :

6

MOLECULAR FORMULA :

C11-H12-N2-O2

MOLECULAR WEIGHT :

204.25

WISWESSER LINE NOTATION :

T56 BMJ D1YZVQ -DL

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

>1 gm/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 15,2134,1966 ** TUMORIGENIC DATA **

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

844 gm/kg/92W-C

TOXIC EFFECTS :

Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors Reproductive - Tumorigenic effects - testicular tumors

REFERENCE :

CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 39,1207,1979 *** REVIEWS *** TOXICOLOGY REVIEW BLFSBY Basic Life Sciences. (Plenum Pub. Corp., 223 Spring St., New York, NY 10003) V.1- 1973- Volume(issue)/page/year: 24,253,1983 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3905 No. of Facilities: 559 (estimated) No. of Industries: 3 No. of Occupations: 11 No. of Employees: 6205 (estimated) No. of Female Employees: 3513 (estimated)

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