Introduction：Basic information about CAS 51865-79-3|D(-)-Amethopterin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | D(-)-Amethopterin |
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| CAS Number | 51865-79-3 | Molecular Weight | 454.439 |
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| Density | 1.537g/cm3 | Boiling Point | / |
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| Molecular Formula | C20H22N8O5 | Melting Point | 195ºC |
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| MSDS | / | Flash Point | / |
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Names
| Name | D-Amethopterin |
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| Synonym | More Synonyms |
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Chemical & Physical Properties
| Density | 1.537g/cm3 |
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| Melting Point | 195ºC |
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| Molecular Formula | C20H22N8O5 |
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| Molecular Weight | 454.439 |
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| Exact Mass | 454.171326 |
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| PSA | 210.54000 |
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| LogP | -0.24 |
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| Index of Refraction | 1.738 |
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| InChIKey | FBOZXECLQNJBKD-CYBMUJFWSA-N |
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| SMILES | CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc1 |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- MA1224000
- CHEMICAL NAME :
- Glutamic acid, N-(p-(((2,4-diamino-6-pteridinyl)methyl)methylamino)b enzoyl)-, D-
- CAS REGISTRY NUMBER :
- 51865-79-3
- LAST UPDATED :
- 199610
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C20-H22-N8-O5
- MOLECULAR WEIGHT :
- 454.50
- WISWESSER LINE NOTATION :
- T66 BN DN GN JNJ CZ EZ H1N1&R DVMYVQ2VQ -D
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 18 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NEOLA4 Neoplasma. (Karger-Libri, P.O. Box, CH-4009 Basel, Switzerland) V.4- 1957- Volume(issue)/page/year: 29,43,1982
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Safety Information
| Risk Phrases | 61-46-25-36/37/38-60-23/24/25 |
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| Safety Phrases | 53-45-28A-36/37/39-26-22 |
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| RIDADR | UN 1544 6.1/PG 3 |
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| HS Code | 29335995 |
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Customs
Synonyms
| DL-Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]- |
| DL-Amethopterin |
| N-(4-{[(2,4-Diamino-6-pteridinyl)methyl](methyl)amino}benzoyl)glutamic acid |
| N-(4-(((2,4-Diamino-6-pteridinyl)methyl)methylamino)benzoyl)-DL-glutamic acid |
| d-methotrexate |
| N-(p-(((2,4-Diamino-6-pteridinyl)methyl)methylamino)benzoyl)-DL-glutamic acid |
| DL-Methotrexate |
| DL-Glutamic acid, N-(4-(((2,4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)- |
| DL-4-Amino-N10-methylpteroylglutamic acid |
| TCMDC-123832 |
| Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]- |
| UNII:99ITO15X8S |
| Einecs 257-482-2 |
| N-(4-{[(2,4-Diaminopteridin-6-yl)methyl](methyl)amino}benzoyl)glutamic acid |
| D(-)-Amethopterin |
| Methotrexate Impurity 6 |
