CAS 129-16-8|Merbromin
Introduction：Basic information about CAS 129-16-8|Merbromin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Merbromin | ||
|---|---|---|---|
| CAS Number | 129-16-8 | Molecular Weight | 752.67 |
| Density | / | Boiling Point | / |
| Molecular Formula | C20H10Br2HgNa2O6 | Melting Point | ≥300 °C |
| MSDS | ChineseUSA | Flash Point | / |
| Symbol | GHS06, GHS08, GHS09 | Signal Word | Danger |
Names
| Name | merbromin |
|---|---|
| Synonym | More Synonyms |
Merbromin BiologicalActivity
| Description | Merbromin is a xanthene dye. |
|---|---|
| Related Catalog | Signaling Pathways >>Anti-infection >>BacterialResearch Areas >>OthersDye Reagents |
Chemical & Physical Properties
| Melting Point | ≥300 °C |
|---|---|
| Molecular Formula | C20H10Br2HgNa2O6 |
| Molecular Weight | 752.67 |
| PSA | 113.63000 |
| LogP | 3.59240 |
| InChIKey | KQSRXDXJGUJRKE-UHFFFAOYSA-L |
| SMILES | O.O=C([O-])c1ccccc1-c1c2cc(Br)c(=O)cc-2oc2c([Hg])c([O-])c(Br)cc12.[Na+].[Na+] |
| Stability | Stable. Incompatible with strong oxidizing agents, strong acids. |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 20 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 50 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 15 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Behavioral - muscle weakness Lungs, Thorax, or Respiration - respiratory stimulation
MUTATION DATA - TYPE OF TEST :
- Sex chromosome loss and nondisjunction
- TEST SYSTEM :
- Yeast - Saccharomyces cerevisiae
- REFERENCE :
- EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 31,97,1979 *** REVIEWS *** TOXICOLOGY REVIEW SDGTB3 Seminars in Drug Treatment. (New York, NY) V.1-3, 1971-74. Discontinued. Volume(issue)/page/year: 1,177,1971 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO MERCURY, ARYL AND INORGANIC-air:CL 0.1 mg/m3 (Sk) REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 44650 No. of Facilities: 586 (estimated) No. of Industries: 5 No. of Occupations: 10 No. of Employees: 7896 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 44650 No. of Facilities: 372 (estimated) No. of Industries: 3 No. of Occupations: 6 No. of Employees: 5294 (estimated) No. of Female Employees: 3955 (estimated)
- TYPE OF TEST :
- Sex chromosome loss and nondisjunction
- TEST SYSTEM :
- Yeast - Saccharomyces cerevisiae
- REFERENCE :
- EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 31,97,1979 *** REVIEWS *** TOXICOLOGY REVIEW SDGTB3 Seminars in Drug Treatment. (New York, NY) V.1-3, 1971-74. Discontinued. Volume(issue)/page/year: 1,177,1971 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO MERCURY, ARYL AND INORGANIC-air:CL 0.1 mg/m3 (Sk) REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 44650 No. of Facilities: 586 (estimated) No. of Industries: 5 No. of Occupations: 10 No. of Employees: 7896 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 44650 No. of Facilities: 372 (estimated) No. of Industries: 3 No. of Occupations: 6 No. of Employees: 5294 (estimated) No. of Female Employees: 3955 (estimated)
Safety Information
| Symbol | GHS06, GHS08, GHS09 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H300 + H310 + H330-H373-H410 |
| Precautionary Statements | P260-P273-P280-P301 + P310 + P330-P302 + P352 + P310-P304 + P340 + P310 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges |
| Hazard Codes | T+:Verytoxic;N:Dangerous for the environment; |
| Risk Phrases | R26/27/28;R33;R50/53 |
| Safety Phrases | S13-S28-S36-S45-S60-S61 |
| RIDADR | UN 2025 6.1/PG 2 |
| WGK Germany | 3 |
| RTECS | LM5250000 |
| Packaging Group | II |
| Hazard Class | 6.1(a) |
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Synonyms
| Broept |
| flavurol |
| Marbromin |
| Emcerol |
| Mercury dibromofluorescein disodium salt |
| gynochrome |
| MFCD00013081 |
| mercurome |
| Chromine |
| domf |
| Ekakrome |
| EINECS 204-933-6 |
