CAS 14807-96-6|Talc

Introduction:Basic information about CAS 14807-96-6|Talc, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameTalc
CAS Number14807-96-6Molecular Weight78.100
Density2.7-2.8 g/cm3Boiling Point/
Molecular FormulaH2O3SiMelting Point800ºC
MSDS/Flash Point/

Names

Namedioxosilane,oxomagnesium,hydrate
SynonymMore Synonyms

Talc BiologicalActivity

DescriptionTalc, a naturally occurring mineral composed primarily of magnesium, silicon and oxygen, is used in many cosmetics, from baby powder to blush[1][2].
Related CatalogResearch Areas >>OthersSignaling Pathways >>Others >>Others
References

[1]. Talc.

[2]. Talc.

Chemical & Physical Properties

Density2.7-2.8 g/cm3
Melting Point800ºC
Molecular FormulaH2O3Si
Molecular Weight78.100
Exact Mass77.977318
PSA197.00000
InChIKeyFPAFDBFIGPHWGO-UHFFFAOYSA-N
SMILESO.O=[Mg].O=[Mg].O=[Mg].O=[Si]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
WW2710000
CHEMICAL NAME :
Talc (powder), containing no asbestos fibers
CAS REGISTRY NUMBER :
14807-96-6
LAST UPDATED :
199712
DATA ITEMS CITED :
31
MOLECULAR FORMULA :
H2-03-Si.3/4Mg
MOLECULAR WEIGHT :
96.33
WISWESSER LINE NOTATION :
.MG4.SI-O3*3

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Human
REFERENCE :
85DKA8 "Cutaneous Toxicity, Proceedings of the 3rd Conference, 1976," Drill, V.A., and P. Lazar, eds., New York, Academic Press, Inc. 1977 Volume(issue)/page/year: -,127,1977 ** TUMORIGENIC DATA **
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
18 mg/m3/6H/2Y-I
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - bronchiogenic carcinoma Endocrine - tumors
REFERENCE :
NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-421,1993
TYPE OF TEST :
TC - Toxic concentration (other than lowest)
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
11 mg/m3/1Y-I
REFERENCE :
43GRAK "Dusts and Disease, Proceedings of the Conference on Occupational Exposures to Fibrous and Particulate Dust and Their Extension into the Environment, 1977," Lemen, R., and J.M. Dement, eds., Park Forest South, IL, Pathotox Pub., 1979 Volume(issue)/page/year: -,389,1979 *** REVIEWS *** ACGIH TLV-Not classifiable as a human carcinogen DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 ACGIH TLV-TWA 2 mg/m3, total dust DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 42,185,1987 IARC Cancer Review:Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 42,185,1987 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,349,1987 *** U.S. STANDARDS AND REGULATIONS *** OSHA PEL (Gen Indu):8H TWA 20 mppcf, respirable dust CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 20 mppcf, respirable dust CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 20 mppcf CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 20 mppcf, respirable dust CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 2.5 mg/m3 JAN 1993 OEL-BELGIUM:TWA 2 mg/m3 JAN 1993 OEL-FINLAND:TWA 5 mg/m3 JAN 1993 OEL-GERMANY:TWA 2 mg/m3 JAN 1993 OEL-SWITZERLAND:TWA 10 mg/m3 (total dust) JAN 1993 OEL-SWITZERLAND:TWA 2 mg/m3 (resp. dust) JAN 1993 OEL-UNITED KINGDOM:TWA 1 mg/m3 (resp. dust) JAN 1993 OEL-UNITED KINGDOM:TWA 10 mg/m3 (total dust) JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO TALC (containing no asbestos)-air:10H 2 mg/m3 REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: PHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 71055 No. of Facilities: 38349 (estimated) No. of Industries: 243 No. of Occupations: 149 No. of Employees: 527353 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X9093 No. of Facilities: 273 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 4245 (estimated) No. of Female Employees: 590 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 71055 No. of Facilities: 82650 (estimated) No. of Industries: 313 No. of Occupations: 192 No. of Employees: 1367384 (estimated) No. of Female Employees: 348973 (estimated)

Safety Information

Hazard CodesXn: Harmful;
Risk PhrasesR20
Safety Phrases36
RTECSWW2710000
HS Code3802900090

Customs

HS Code3802900090

Synonyms

Hydrous magnesium silicate,Talc
S1900_Selleck
Hydrous magnesium silicate,Talcum
talcum powder
MFCD00792903
magnesium hydrosilicate
EINECS 238-877-9
French chalk
oxosilanediol
Hydrous magnesium silicate
micronized talc
Talc
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