CAS 110764-79-9|2'-O-Methyl Uridine CED Phosphoramidite

Introduction:Basic information about CAS 110764-79-9|2'-O-Methyl Uridine CED Phosphoramidite, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name2'-O-Methyl Uridine CED Phosphoramidite
CAS Number110764-79-9Molecular Weight760.81200
Density/Boiling Point/
Molecular FormulaC40H49N4O9PMelting Point/
MSDSUSAFlash Point/

Names

NameDMT-2′O-Methyl-rU Phosphoramidite
SynonymMore Synonyms

2'-O-Methyl Uridine CED Phosphoramidite BiologicalActivity

DescriptionDMT-2'O-Methyl-rU Phosphoramidite (2'-O-Me-U Phosphoramidite) is a 2'-O-Me derivative, and can be used for oligonucleotide synthesis[1][2].
Related CatalogResearch Areas >>OthersSignaling Pathways >>Others >>Others
References

[1]. Stump MD, et al. The use of modified primers to eliminate cycle sequencing artifacts. Nucleic Acids Res. 1999 Dec 1;27(23):4642-8.

[2]. Takahashi M, et al. Synthesis and characterization of 2'-modified-4'-thioRNA: a comprehensive comparison of nuclease stability. Nucleic Acids Res. 2009 Mar;37(4):1353-62.

Chemical & Physical Properties

Molecular FormulaC40H49N4O9P
Molecular Weight760.81200
Exact Mass760.32400
PSA160.09000
LogP6.13608
InChIKeyUVUOJOLPNDCIHL-XKZJCBTISA-N
SMILESCOc1ccc(C(OCC2OC(n3ccc(=O)[nH]c3=O)C(OC)C2OP(OCCC#N)N(C(C)C)C(C)C)(c2ccccc2)c2ccc(OC)cc2)cc1

Safety Information

Personal Protective EquipmentEyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADRNONH for all modes of transport

Synonyms

3-[[(2R,3R,4R,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-5-(2,4-dioxopyrimidin-1-yl)-4-methoxyoxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile
2'-O-Methyl Uridine CED Phosphoramidite
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