CAS 75847-73-3|Enalapril
Introduction：Basic information about CAS 75847-73-3|Enalapril, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Enalapril | ||
|---|---|---|---|
| CAS Number | 75847-73-3 | Molecular Weight | 376.447 |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 582.3±50.0 °C at 760 mmHg |
| Molecular Formula | C20H28N2O5 | Melting Point | 143-144.5ºC |
| MSDS | USA | Flash Point | 306.0±30.1 °C |
| Symbol | GHS07, GHS08 | Signal Word | Warning |
Names
| Name | enalapril |
|---|---|
| Synonym | More Synonyms |
Enalapril BiologicalActivity
| Description | Enalapril is an angiotensin converting enzyme (ACE) inhibitorTarget: ACEEnalapril belongs to a class of medications called angiotensin converting enzyme inhibitors. Normally angiotensin I is converted to angiotensin II by angiotensin converting enzyme (ACE). Angiotensin II constricts blood vessels, increasing blood pressure. By inhibiting ACE, Enalapril decreases levels of angiotensin II leading to less vasoconstriction and decreased blood pressure. |
|---|---|
| Related Catalog | Signaling Pathways >>Metabolic Enzyme/Protease >>Angiotensin-converting Enzyme (ACE)Natural Products >>OthersResearch Areas >>Cardiovascular Disease |
| References | [1]. http://en.wikipedia.org/wiki/Enalapril |
Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 582.3±50.0 °C at 760 mmHg |
| Melting Point | 143-144.5ºC |
| Molecular Formula | C20H28N2O5 |
| Molecular Weight | 376.447 |
| Flash Point | 306.0±30.1 °C |
| Exact Mass | 376.199829 |
| PSA | 170.54000 |
| LogP | 2.43 |
| Vapour Pressure | 0.0±1.7 mmHg at 25°C |
| Index of Refraction | 1.550 |
| InChIKey | GBXSMTUPTTWBMN-XIRDDKMYSA-N |
| SMILES | CCOC(=O)C(CCc1ccccc1)NC(C)C(=O)N1CCCC1C(=O)O |
Safety Information
| Symbol | GHS07, GHS08 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H317-H361 |
| Precautionary Statements | P280 |
| Hazard Codes | Xi |
| Safety Phrases | S22-S24/25 |
| RIDADR | NONH for all modes of transport |
| RTECS | TW3665500 |
Articles119
More Articles| Evaluation of a rapid method for the therapeutic drug monitoring of aliskiren, enalapril and its active metabolite in plasma and urine by UHPLC-MS/MS. J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 980 , 79-87, (2015) Given the increasing popularity of aliskiren, particularly in combination with angiotensin converting enzyme inhibitor (e.g. enalapril), it is important to determine whether its use in combination wit... | |
| Mineralocorticoid receptor blockade improves coronary microvascular function in individuals with type 2 diabetes. Diabetes 64(1) , 236-42, (2015) Reduced coronary flow reserve (CFR), an indicator of coronary microvascular dysfunction, is seen in type 2 diabetes mellitus (T2DM) and predicts cardiac mortality. Since aldosterone plays a key role i... | |
| Critical blood pressure threshold dependence of hypertensive injury and repair in a malignant nephrosclerosis model. Hypertension 64(4) , 801-7, (2014) Most patients with essential hypertension do not exhibit substantial renal damage. Renal autoregulation by preventing glomerular transmission of systemic pressures has been postulated to mediate this ... |
Synonyms
| Enacard |
| [3H]-Eletriptan |
| N-[(S)-1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl-L-proline |
| Eletriptan [INN:BAN] |
| Acesistem |
| Eletriptan |
| Lotrial |
| EINECS 278-375-7 |
| Naprilene |
| (R)-5-(2-phenylsulphonylethyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole |
| L-Proline, N-((1S)-1-(ethoxycarbonyl)-3-phenylpropyl)-L-alanyl- |
| Enalapril |
| 1-[N-[(S)-1-Carboxy-3-phenylpropyl]-1-alanyl]-L-proline 1'-Ethyl Ester |
| enalaprila |
| MFCD00865774 |
| N-{(1S)-1-[(ethyloxy)carbonyl]-3-phenylpropyl}-L-alanyl-L-proline |
| Reniten |
| N-[(2S)-1-Ethoxy-1-oxo-4-phenyl-2-butanyl]alanyl-L-proline |
| Eletriptan (INN) |
| Enap |
| Renitec |
| N-[1-(S)-(ethoxycarbonyl)-3-phenylpropyl]alanylproline |
| 3-(N-methyl-2(R)-pyrrolidinylmethyl)-5-(2-phenylsulphonylethyl)-1H-indole |
| Hipoartel |
| Amprace |
| Relpax |
| olivin |
| Xanef |
| N-[(2S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl]-L-alanyl-L-proline |
| eletriptanum |
| L-Proline, N-[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]alanyl- |
| Enapren |
| N-[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl-L-proline |
| Enaloc |
| Renivace |
| Glioten |
| L-Proline, N-[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl- |
| N-[(2S)-1-Ethoxy-1-oxo-4-phenyl-2-butanyl]-L-alanyl-L-proline |
| Pres |
| Innovace |
| (R)-3-((1-methylpyrrolidin-2-yl)methyl)-5-(2-(phenylsulfonyl)ethyl)-1H-indole |
