Introduction：Basic information about CAS 91366-65-3|ABD-F, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | ABD-F |
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| CAS Number | 91366-65-3 | Molecular Weight | 217.178 |
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| Density | 1.7±0.1 g/cm3 | Boiling Point | 408.8±55.0 °C at 760 mmHg |
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| Molecular Formula | C6H4FN3O3S | Melting Point | 145-146ºC |
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| MSDS | USA | Flash Point | 201.0±31.5 °C |
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Names
| Name | 4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole |
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| Synonym | More Synonyms |
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ABD-F BiologicalActivity
| Description | 4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole (ABD-F) is a fluorescent reagent for the sensitive and specific detection of thiols. 4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole has low fluorescence background, and good stability of fluorophor[1]. |
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| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
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| References | [1]. Toyooka T, et al. New fluorogenic reagent having halogenobenzofurazan structure for thiols: 4-(aminosulfonyl)-7-fluoro-2, 1, 3-benzoxadiazole. Analytical chemistry, 1984, 56(13): 2461-2464. |
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Chemical & Physical Properties
| Density | 1.7±0.1 g/cm3 |
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| Boiling Point | 408.8±55.0 °C at 760 mmHg |
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| Melting Point | 145-146ºC |
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| Molecular Formula | C6H4FN3O3S |
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| Molecular Weight | 217.178 |
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| Flash Point | 201.0±31.5 °C |
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| Exact Mass | 216.995743 |
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| PSA | 107.46000 |
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| LogP | 0.11 |
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| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
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| Index of Refraction | 1.632 |
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| InChIKey | XROXHZMRDABMHS-UHFFFAOYSA-N |
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| SMILES | NS(=O)(=O)c1ccc(F)c2nonc12 |
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| Storage condition | −20°C |
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| Stability | Light Sensitive |
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| Water Solubility | DMSO: soluble |
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Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| Hazard Codes | Xi: Irritant; |
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| Risk Phrases | 20/21/22-36/37/38 |
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| Safety Phrases | 26-36/37/39 |
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| RIDADR | NONH for all modes of transport |
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| WGK Germany | 3 |
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| HS Code | 2935009090 |
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Customs
| HS Code | 2935009090 |
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| Summary | 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0% |
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Articles28
More Articles
| Quantification of glutathione in plasma samples by HPLC using 4-fluoro-7-nitrobenzofurazan as a fluorescent labeling reagent. J. Chromatogr. Sci. 50 , 119-122, (2012) A rapid and highly sensitive high-performance liquid chromatograpy method with fluorescence detection has been developed for determination of glutathione (GSH) in human plasma. A simple pre-column der... | |
| Plasma thiols levels in Alzheimer's disease mice under diet-induced hyperhomocysteinemia: effect of S-adenosylmethionine and superoxide-dismutase supplementation. J. Alzheimers Dis. 44(4) , 1323-31, (2015) Widely confirmed reports were published on association between hyperhomocysteinemia, B vitamin deficiency, oxidative stress, and amyloid-β in Alzheimer's disease (AD). Homocysteine, cysteine, cysteiny... | |
| Allosteric inhibition of PTP1B activity by selective modification of a non-active site cysteine residue. Biochemistry 44(21) , 7704-12, (2005) The fluorogenic reagent 4-(aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole (ABDF) attenuates the functional activity of the protein tyrosine phosphatase PTP1B by reacting selectively with a single cystei... | |
Synonyms
| 7-Fluoro-2,1,3-benzoxadiazole-4-sulfonamide |
| 2,1,3-Benzoxadiazole-4-sulfonamide, 7-fluoro- |
| MFCD00036687 |
