CAS 9002-13-5|Urea
| Common Name | Urea | ||
|---|---|---|---|
| CAS Number | 9002-13-5 | Molecular Weight | 60.055 |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 165.1±23.0 °C at 760 mmHg |
| Molecular Formula | C2H6 | Melting Point | / |
| MSDS | ChineseUSA | Flash Point | 53.7±22.6 °C |
| Symbol | GHS07, GHS08 | Signal Word | Danger |
Names
| Name | Ethane |
|---|---|
| Synonym | More Synonyms |
Urea BiologicalActivity
| Description | Urease is produced by many types of bacteria and is an effective virulence factor for some pathogenic bacteria. Urease is also central to the metabolism and virulence of Helicobacter pylori, helping it colonize the stomach lining[1]. |
|---|---|
| Related Catalog | Research Areas >>OthersSignaling Pathways >>Anti-infection >>Bacterial |
| References | [1]. Mobley H L T, et al. Urease[J]. Helicobacter pylori: physiology and genetics, 2001: 177-191. |
Chemical & Physical Properties
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 165.1±23.0 °C at 760 mmHg |
| Molecular Formula | C2H6 |
| Molecular Weight | 60.055 |
| Flash Point | 53.7±22.6 °C |
| Exact Mass | 60.032364 |
| LogP | -1.43 |
| Vapour Pressure | 0.6±0.7 mmHg at 25°C |
| Index of Refraction | 1.528 |
| Storage condition | 2-8°C |
| Water Solubility | It is slightly soluble in water. |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 48 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - lacrimation Behavioral - sleep Kidney, Ureter, Bladder - urine volume increased
- REFERENCE :
- AJPHAP American Journal of Physiology. (American Physiological Soc., 9650 Rockville Pike, Bethesda, MD 20814) V.1- 1898- Volume(issue)/page/year: 206,731,1964
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 20 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- AJPHAP American Journal of Physiology. (American Physiological Soc., 9650 Rockville Pike, Bethesda, MD 20814) V.1- 1898- Volume(issue)/page/year: 206,731,1964
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 50 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - lacrimation Behavioral - sleep Kidney, Ureter, Bladder - urine volume increased
- REFERENCE :
- AJPHAP American Journal of Physiology. (American Physiological Soc., 9650 Rockville Pike, Bethesda, MD 20814) V.1- 1898- Volume(issue)/page/year: 206,731,1964
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 58 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AJPHAP American Journal of Physiology. (American Physiological Soc., 9650 Rockville Pike, Bethesda, MD 20814) V.1- 1898- Volume(issue)/page/year: 206,731,1964
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 25 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - lacrimation Behavioral - sleep Kidney, Ureter, Bladder - urine volume increased
- REFERENCE :
- AJPHAP American Journal of Physiology. (American Physiological Soc., 9650 Rockville Pike, Bethesda, MD 20814) V.1- 1898- Volume(issue)/page/year: 206,731,1964
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 6 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- AJPHAP American Journal of Physiology. (American Physiological Soc., 9650 Rockville Pike, Bethesda, MD 20814) V.1- 1898- Volume(issue)/page/year: 206,731,1964
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 35 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - lacrimation Behavioral - sleep Kidney, Ureter, Bladder - urine volume increased
- REFERENCE :
- AJPHAP American Journal of Physiology. (American Physiological Soc., 9650 Rockville Pike, Bethesda, MD 20814) V.1- 1898- Volume(issue)/page/year: 206,731,1964 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3123 No. of Facilities: 1133 (estimated) No. of Industries: 3 No. of Occupations: 9 No. of Employees: 14585 (estimated) No. of Female Employees: 9975 (estimated)
Safety Information
| Symbol | GHS07, GHS08 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H315-H319-H334-H335 |
| Precautionary Statements | P261-P305 + P351 + P338-P342 + P311 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Faceshields;Gloves |
| Hazard Codes | Xn |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S22-S24-S26-S36/37-S45-S36-S23 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 1 |
| RTECS | YU1700000 |
Articles59
More Articles| Efficiency of utilization of nitrogen coated with urease inhibitor in maize. Pak. J. Biol. Sci. 16(17) , 871-6, (2013) This study aimed to evaluate under field conditions the efficiency in the use ofN coated with urease inhibitor in maize. The experiment was conducted in the year of 2007/2008. The experimental design ... | |
| Study of alpha-amylase and urease inhibitory activities of Melilotus indicus (Linn.) All. Pak. J. Pharm. Sci. 27(1) , 57-61, (2014) Melilotus indicus (Linn.) All. is a small herb distributed throughout Pakistan and has a number of ethnomedicinal uses. It is also consumed as a vegetable. In the present work, we are reporting the al... | |
| Effects of the halophytes Tecticornia indica and Suaeda fruticosa on soil enzyme activities in a Mediterranean Sabkha. Int. J. Phytoremediation 15(2) , 188-97, (2013) In the present work, we studied the effectiveness of the predominant halophytes of Soliman sabkha (Tecticornia indica and Suaeda fruticosa) to promote soil biological activities and ecosystem producti... |
Synonyms
| Carbonyl diamide |
| Urea |
| Carbamide |
| carbonyl diamine |
| MFCD00070858 |
| Urea (8CI,9CI) |
