CAS 517-63-5|stephanine

Introduction：Basic information about CAS 517-63-5|stephanine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. stephanine BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	stephanine
CAS Number	517-63-5	Molecular Weight	309.36
Density	1.3±0.1 g/cm3	Boiling Point	463.6±45.0 °C at 760 mmHg
Molecular Formula	C₁₉H₁₉NO₃	Melting Point	/
MSDS	/	Flash Point	140.4±25.9 °C

Names

Name	(7aR)-9-Methoxy-7-methyl-6,7,7a,8-tetrahydro-5H-[1,3]benzodioxolo [6,5,4-de]benzo[g]quinoline
Synonym	More Synonyms

stephanine BiologicalActivity

Description	Stephanine ((-)-Stephanine) is an isoquinoline aporphine-type alkaloid. Stephanine induce apoptosis through the reverse of mitotic exit. Stephanine exhibits Antiplasmodial activity. Stephanine can be used for the research of stomach pain, abdominal pain, arthritis and cancer[1][2].
Related Catalog	Signaling Pathways >>Apoptosis >>ApoptosisResearch Areas >>CancerResearch Areas >>InfectionResearch Areas >>Inflammation/Immunology
References	[1]. Cui L, et, al. The anti-inflammatory and analgesic activities of 2Br-Crebanine and Stephanine from Stephania yunnanenses H. S.Lo. Front Pharmacol. 2023 Jan 4;13:1092583. [2]. Le PM, et, al. Stephanine from Stephania venosa (Blume) Spreng Showed Effective Antiplasmodial and Anticancer Activities, the Latter by Inducing Apoptosis through the Reverse of Mitotic Exit. Phytother Res. 2017 Sep;31(9):1357-1368.

Description

Stephanine ((-)-Stephanine) is an isoquinoline aporphine-type alkaloid. Stephanine induce apoptosis through the reverse of mitotic exit. Stephanine exhibits Antiplasmodial activity. Stephanine can be used for the research of stomach pain, abdominal pain, arthritis and cancer[1][2].

Related Catalog

Signaling Pathways >>Apoptosis >>ApoptosisResearch Areas >>CancerResearch Areas >>InfectionResearch Areas >>Inflammation/Immunology

References

[1]. Cui L, et, al. The anti-inflammatory and analgesic activities of 2Br-Crebanine and Stephanine from Stephania yunnanenses H. S.Lo. Front Pharmacol. 2023 Jan 4;13:1092583.

[2]. Le PM, et, al. Stephanine from Stephania venosa (Blume) Spreng Showed Effective Antiplasmodial and Anticancer Activities, the Latter by Inducing Apoptosis through the Reverse of Mitotic Exit. Phytother Res. 2017 Sep;31(9):1357-1368.

Chemical & Physical Properties

Density	1.3±0.1 g/cm3
Boiling Point	463.6±45.0 °C at 760 mmHg
Molecular Formula	C₁₉H₁₉NO₃
Molecular Weight	309.36
Flash Point	140.4±25.9 °C
Exact Mass	309.136505
PSA	30.93000
LogP	4.16
Vapour Pressure	0.0±1.1 mmHg at 25°C
Index of Refraction	1.631
InChIKey	UEAPAHNNFSZHMW-CQSZACIVSA-N
SMILES	COc1cccc2c1CC1c3c(cc4c(c3-2)OCO4)CCN1C

Safety Information

Hazard Codes	Xi

Synonyms

5H-1,3-Benzodioxolo[6,5,4-de]benzo[g]quinoline, 6,7,7a,8-tetrahydro-9-methoxy-7-methyl-, (7aR)-

(7aR)-9-Methoxy-7-methyl-6,7,7a,8-tetrahydro-5H-[1,3]benzodioxolo[6,5,4-de]benzo[g]quinoline

5H-Benzo(g)-1,3-benzodioxolo(6,5,4-de)quinoline, 6,7,7a,8-tetrahydro-9-methoxy-7-methyl-, (R)-

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