Introduction：Basic information about CAS 80508-42-5|Tenacigenin B, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Tenacigenin B |
|---|
| CAS Number | 80508-42-5 | Molecular Weight | 364.48 |
|---|
| Density | 1.3±0.1 g/cm3 | Boiling Point | 537.2±50.0 °C at 760 mmHg |
|---|
| Molecular Formula | C21H32O5 | Melting Point | / |
|---|
| MSDS | / | Flash Point | 187.2±23.6 °C |
|---|
Names
| Name | (3β,5α,11α,12β,14β,17α)-3,11,12-Trihydroxy-8,14-epoxypregnan-20-o ne |
|---|
| Synonym | More Synonyms |
|---|
Tenacigenin B BiologicalActivity
| Description | Tenacigenin B is a steroid that can be isolated from the genus Alocasia. Tenacigenin B has anti-tumor effects on lymphoma via regulation of Aurora-A[1][2]. |
|---|
| Related Catalog | Signaling Pathways >>Epigenetics >>Aurora KinaseResearch Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Aurora Kinase |
|---|
| References | [1]. Peng W, et al. The cytotoxic and tyrosine kinase inhibitory properties of C21 steroids and iridoids from the tubers of Alocasia cucullata. J Nat Med. 2016 Jul;70(3):602-9. [2]. Dai X, et al. Tenacigenin B Has Anti-Tumor Effect in Lymphoma by In Vitro and In Vivo Study. Med Sci Monit. 2019 Sep 1;25:6563-6573. |
|---|
Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
|---|
| Boiling Point | 537.2±50.0 °C at 760 mmHg |
|---|
| Molecular Formula | C21H32O5 |
|---|
| Molecular Weight | 364.48 |
|---|
| Flash Point | 187.2±23.6 °C |
|---|
| Exact Mass | 364.224976 |
|---|
| PSA | 90.29000 |
|---|
| LogP | 1.50 |
|---|
| Vapour Pressure | 0.0±3.2 mmHg at 25°C |
|---|
| Index of Refraction | 1.597 |
|---|
| InChIKey | FWXVLSDGEDMLQU-UYLIPJATSA-N |
|---|
| SMILES | CC(=O)C1CCC23OC24CCC2CC(O)CCC2(C)C4C(O)C(O)C13C |
|---|
Safety Information
Synonyms
| (3β,5α,11α,12β,14β,17α)-3,11,12-Trihydroxy-8,14-epoxypregnan-20-one |
| Pregnan-20-one, 8,14-epoxy-3,11,12-trihydroxy-, (3β,5α,11α,12β,14β,17α)- |
