CAS 40456-50-6|Yatein

Introduction：Basic information about CAS 40456-50-6|Yatein, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Yatein BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	Yatein
CAS Number	40456-50-6	Molecular Weight	400.422
Density	1.3±0.1 g/cm3	Boiling Point	564.9±45.0 °C at 760 mmHg
Molecular Formula	C₂₂H₂₄O₇	Melting Point	/
MSDS	/	Flash Point	246.2±28.8 °C

Names

Name	(3R,4R)-4-(1,3-benzodioxol-5-ylmethyl)-3-[(3,4,5-trimethoxyphenyl)methyl]oxolan-2-one
Synonym	More Synonyms

Yatein BiologicalActivity

Description	Yatein is a lignan isolated from A. chilensis, with antiproliferative activity[1]. Yatein suppresses herpes simplex virus type 1 (HSV-1 ) replication by interruption the immediate-early gene expression[2].
Related Catalog	Research Areas >>CancerSignaling Pathways >>Anti-infection >>HSVResearch Areas >>Infection
References	[1]. Donoso-Fierro C, et al. Antiproliferative activity of yatein isolated from Austrocedrus chilensis against murine myeloma cells: cytological studies and chemical investigations. Pharm Biol. 2015 Mar;53(3):378-85. [2]. Kuo YC, et al. Yatein from Chamaecyparis obtusa suppresses herpes simplex virus type 1 replication in HeLa cells by interruption the immediate-early gene expression. Antiviral Res. 2006 Jul;70(3):112-20.

Description

Yatein is a lignan isolated from A. chilensis, with antiproliferative activity[1]. Yatein suppresses herpes simplex virus type 1 (HSV-1 ) replication by interruption the immediate-early gene expression[2].

Related Catalog

Research Areas >>CancerSignaling Pathways >>Anti-infection >>HSVResearch Areas >>Infection

References

[1]. Donoso-Fierro C, et al. Antiproliferative activity of yatein isolated from Austrocedrus chilensis against murine myeloma cells: cytological studies and chemical investigations. Pharm Biol. 2015 Mar;53(3):378-85.

[2]. Kuo YC, et al. Yatein from Chamaecyparis obtusa suppresses herpes simplex virus type 1 replication in HeLa cells by interruption the immediate-early gene expression. Antiviral Res. 2006 Jul;70(3):112-20.

Chemical & Physical Properties

Density	1.3±0.1 g/cm3
Boiling Point	564.9±45.0 °C at 760 mmHg
Molecular Formula	C₂₂H₂₄O₇
Molecular Weight	400.422
Flash Point	246.2±28.8 °C
Exact Mass	400.152191
PSA	72.45000
LogP	3.06
Vapour Pressure	0.0±1.5 mmHg at 25°C
Index of Refraction	1.577
InChIKey	GMLDZDDTZKXJLU-JKSUJKDBSA-N
SMILES	COc1cc(CC2C(=O)OCC2Cc2ccc3c(c2)OCO3)cc(OC)c1OC

Synonyms

Yatein

(3R,4R)-4-(1,3-Benzodioxol-5-ylmethyl)-3-(3,4,5-trimethoxybenzyl)dihydro-2(3H)-furanone

(3R,4R)-4-(1,3-Benzodioxol-5-ylmethyl)-3-(3,4,5-trimethoxybenzyl)dihydrofuran-2(3H)-one

Deoxypodorhizone

Dihydroanhydropodorhizol

2(3H)-Furanone, 4-(1,3-benzodioxol-5-ylmethyl)dihydro-3-[(3,4,5-trimethoxyphenyl)methyl]-, (3R,4R)-

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