Introduction：Basic information about CAS 3583-64-0|Bumadizone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Bumadizone |
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| CAS Number | 3583-64-0 | Molecular Weight | 326.39000 |
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| Density | 1.227g/cm3 | Boiling Point | 487.4ºC at 760mmHg |
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| Molecular Formula | C19H22N2O3 | Melting Point | / |
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| MSDS | / | Flash Point | 248.6ºC |
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Names
| Name | bumadizone |
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| Synonym | More Synonyms |
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Bumadizone BiologicalActivity
| Description | Bumadizone is a non-steroidal anti-inflammatory drug (NSAID) and can relieve pain[1]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology |
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| In Vitro | Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used in the chronic inflammatoryconditions. |
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| References | [1]. Samia A Nour, et al. Bumadizone calcium dihydrate microspheres compressed tablets for colon targeting: formulation, optimization and in vivo evaluation in rabbits. Drug Deliv. 2015 May;22(3):286-97. |
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Chemical & Physical Properties
| Density | 1.227g/cm3 |
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| Boiling Point | 487.4ºC at 760mmHg |
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| Molecular Formula | C19H22N2O3 |
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| Molecular Weight | 326.39000 |
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| Flash Point | 248.6ºC |
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| Exact Mass | 326.16300 |
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| PSA | 69.64000 |
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| LogP | 4.01070 |
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| Index of Refraction | 1.628 |
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| InChIKey | FLWFHHFTIRLFPV-UHFFFAOYSA-N |
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| SMILES | CCCCC(C(=O)O)C(=O)N(Nc1ccccc1)c1ccccc1 |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- OO0623000
- CHEMICAL NAME :
- Malonic acid, butyl-, mono(1,2-diphenylhydrazide)
- CAS REGISTRY NUMBER :
- 3583-64-0
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C19-H22-N2-O3
- MOLECULAR WEIGHT :
- 326.43
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1350 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 67,337,1971
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 270 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 67,337,1971
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Safety Information
Customs
| HS Code | 2928000090 |
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| Summary | 2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0% |
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Synonyms
| Butyramide,N-sec-butyl |
| (+-)-Buttersaeure-sec-butylamid |
| 2-[(1,2-Diphenylhydrazino)carbonyl]hexanoic acid |
| Butanamide,N-(1-methylpropyl) |
| N-(2-Carboxy-hexanoyl)-hydrazobenzol |
| N-s-Butyl-butyramide |
| N-sec-butyl-butyramide |
| N-(2-carboxycaproyl)hydrazobenzene |
| N-(2-BUTYL)BUTANAMIDE |
| Bumadizon (14C) |
| Butylmalonsaeure-N,N'-diphenylmonohydrazid |
| (+-)-Butylmalonsaeure-mono-<N.N'-diphenyl-hydrazid> |
