CAS 918430-49-6|3,5-Dichloro-N-((1-((2,2-dimethyltetrahydro-2H-pyran-4-yl)methyl)-4-fluoropiperidin-

Introduction：Basic information about CAS 918430-49-6|3,5-Dichloro-N-((1-((2,2-dimethyltetrahydro-2H-pyran-4-yl)methyl)-4-fluoropiperidin-, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	3,5-Dichloro-N-((1-((2,2-dimethyltetrahydro-2H-pyran-4-yl)methyl)-4-fluoropiperidin-4-yl)methyl)benzamide
CAS Number	918430-49-6	Molecular Weight	431.37
Density	1.25g/cm3	Boiling Point	510.1°C at 760 mmHg
Molecular Formula	C₂₁H₂₉Cl₂FN₂O₂	Melting Point	/
MSDS	/	Flash Point	262.3°C

Names

Name	3,5-Dichloro-N-({1-[(2,2-dimethyltetrahydro-2H-pyran-4-yl)methyl] -4-fluoro-4-piperidinyl}methyl)benzamide
Synonym	More Synonyms

BiologicalActivity

Description	(Rac)-TTA-P2 is the inactive isomer of TTA-P2 (HY-10035), and can be used as an experimental control. TTA-P2 (T-Type calcium channel inhibitor) is a potent inhibitor of T-Type calcium channel. TTA-P2 penetrates well the CNS and blocks the native T-type currents in deep cerebellar nuclear neurons, the window current is completely abolished both for wild-type and mutant Cav3.1 channels. TTA-P2 has the potential for the research of neurology disease[1].
Related Catalog	Signaling Pathways >>Others >>OthersResearch Areas >>Neurological Disease
References	[1]. M R Hellberg, et al. Preclinical efficacy of travoprost, a potent and selective FP prostaglandin receptor agonist. J Ocul Pharmacol Ther. 2001 Oct;17(5):421-32.

Chemical & Physical Properties

Density	1.25g/cm3
Boiling Point	510.1°C at 760 mmHg
Molecular Formula	C₂₁H₂₉Cl₂FN₂O₂
Molecular Weight	431.37
Flash Point	262.3°C
Exact Mass	430.15900
PSA	45.06000
LogP	5.24520
InChIKey	DKNDOKIVCXTFHJ-UHFFFAOYSA-N
SMILES	CC1(C)CC(CN2CCC(F)(CNC(=O)c3cc(Cl)cc(Cl)c3)CC2)CCO1

Synonyms

MFCD11977740

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