CAS 51-85-4|Cystamine

Introduction:Basic information about CAS 51-85-4|Cystamine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameCystamine
CAS Number51-85-4Molecular Weight152.28100
Density1.172g/cm3Boiling Point264.8ºC at 760 mmHg
Molecular FormulaC4H12N2S2Melting Point/
MSDS/Flash Point114ºC

Names

Namecystamine
SynonymMore Synonyms

Cystamine BiologicalActivity

DescriptionCystamine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker
Target

Alkyl-Chain

In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Chemical & Physical Properties

Density1.172g/cm3
Boiling Point264.8ºC at 760 mmHg
Molecular FormulaC4H12N2S2
Molecular Weight152.28100
Flash Point114ºC
Exact Mass152.04400
PSA102.64000
LogP1.68580
Index of Refraction1.587
InChIKeyAPQPRKLAWCIJEK-UHFFFAOYSA-N
SMILESNCCSSCCN

Safety Information

HS Code2930909090

Customs

HS Code2930909090
Summary2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Synonyms

diaminosulphonate
NH2CH2CH2NHCH2CH2SO3Na
cysteamine disulfide
2-[(2-aminoethyl)amino]-ethanesulfonic acid monosodium salt
SodiuM 2-[(2-aMinoethyl)aMino]ethanesulphona
2-(2-aminoethyldisulfanyl)ethanamine
Natrium-2-[(2-aminoethyl)amino]ethansulfonat
N-(2-AMINOETHYL)-3-AMINOETHANESULPHONICACID,SODIUMSALT
2,2'-Disulfanediyldiethanamine
3,4-dithiahexane-1,6-diamine
2-[(2-Aminoethyl)amino]ethane-1-sulfonic acid sodium salt
2-(2-aminoethyldisulfonyl)-ethylamine
Ethanesulfonic acid,2-(2-aminoethyl)amino-,monosodium salt
sodium salt of 2-(2-amino-ethylamino)-ethanesulfonic acid
2-[(2-AMINOETHYL)AMINO]ETHANE SULFONIC ACID SODIUM SALT
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