Introduction：Basic information about CAS 122830-14-2|Deriglidole, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Deriglidole |
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| CAS Number | 122830-14-2 | Molecular Weight | 255.35800 |
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| Density | 1.27g/cm3 | Boiling Point | 456.4ºC at 760mmHg |
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| Molecular Formula | C16H21N3 | Melting Point | / |
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| MSDS | / | Flash Point | 229.8ºC |
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Names
| Name | Deriglidole |
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| Synonym | More Synonyms |
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Deriglidole BiologicalActivity
| Description | Deriglidole is a peripheral adrenoceptor antagonist with a high affinity for α2-adrenoceptors. |
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| Related Catalog | Signaling Pathways >>GPCR/G Protein >>Adrenergic ReceptorResearch Areas >>Metabolic Disease |
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| Target | Adrenoceptor[1] |
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| In Vitro | Deriglidole is a selective α2-receptor inhibitor. Deriglidole inhibits [3H]Clonidine and [3H]Idazoxan but not [3H]Prazosin binding to rat cortical and human platelet α2-adrenoceptors and is more selective than Idazoxan for peripheral receptors[1]. |
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| References | [1]. Natali A, et al. Effects of acute alpha 2-blockade on insulin action and secretion in humans. Am J Physiol. 1998 Jan;274(1 Pt 1):E57-64. |
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Chemical & Physical Properties
| Density | 1.27g/cm3 |
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| Boiling Point | 456.4ºC at 760mmHg |
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| Molecular Formula | C16H21N3 |
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| Molecular Weight | 255.35800 |
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| Flash Point | 229.8ºC |
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| Exact Mass | 255.17400 |
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| PSA | 27.63000 |
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| LogP | 1.97520 |
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| Vapour Pressure | 1.62E-08mmHg at 25°C |
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| Index of Refraction | 1.686 |
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| InChIKey | BADQRNHAZHSOKC-UHFFFAOYSA-N |
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| SMILES | CCCC1(C2=NCCN2)Cc2cccc3c2N1CC3 |
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| Storage condition | 2-8℃ |
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Synonyms
| (+)-1,2,4,5-Tetrahydro-2-(2-imidazolin-2-yl)-2-propylpyrrolo(3,2,1-hi)indole |
| UNII-68EP8R4PMV |
| 2-(4,5-dihydro-1h-imidazol-2-yl)-2-propyl-1,2,4,5-tetrahydropyrrolo[3,2,1-hi]indole |
