Introduction：Basic information about CAS 852433-84-2|Dovitinib (TKI-258) Dilactic Acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Dovitinib (TKI-258) Dilactic Acid |
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| CAS Number | 852433-84-2 | Molecular Weight | 572.59 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C27H33FN6O7 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 2-Hydroxypropanoic acid-4-amino-5-fluoro-3-[5-(4-methyl-1-piper azinyl)-1H-benzimidazol-2-yl]-2(1H)-quinolinone (2:1) |
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| Synonym | More Synonyms |
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Dovitinib (TKI-258) Dilactic Acid BiologicalActivity
| Description | Dovitinib (dilactic acid) is an orally active inhibitor of VEGF kinase. Dovitinib (dilactic acid) inhibits receptor tyrosine kinases (RTKs) involved in solid and hematologic cancers and tumor angiogenesis[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Protein Tyrosine Kinase/RTK >>VEGFR |
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| References | [1]. Zhu, S., et al. The Chemical Development of CHIR-258. CHIMIA International Journal for Chemistry, 60(9), 584–592. |
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Chemical & Physical Properties
| Molecular Formula | C27H33FN6O7 |
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| Molecular Weight | 572.59 |
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| Exact Mass | 572.239502 |
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| PSA | 209.36000 |
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| LogP | 2.44450 |
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| InChIKey | XXLPVQZYQCGXOV-UHFFFAOYSA-N |
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| SMILES | CC(O)C(=O)O.CC(O)C(=O)O.CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 |
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| Storage condition | -20℃ |
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Synonyms
| Dovitinib (TKI-258) Dilactic Acid |
| Propanoic acid, 2-hydroxy-, compd. with 4-amino-5-fluoro-3-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-2(1H)-quinolinone (2:1) |
| Dovitinib Dilactic acid |
| 2-Hydroxypropanoic acid - 4-amino-5-fluoro-3-[5-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-2(1H)-quinolinone (2:1) |
| TKI258 Dilactic acid |
| Dovitinib Dilacticacid |
