Introduction：Basic information about CAS 1207456-00-5|BMN-673 (8R,9S), including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | BMN-673 (8R,9S) |
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| CAS Number | 1207456-00-5 | Molecular Weight | 380.35100 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C19H14F2N6O | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | (8R,9S)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-8,9-dihydro-2H-pyrido[4,3 ,2-de] phthalazin-3(7H)-one |
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| Synonym | More Synonyms |
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BMN-673 (8R,9S) BiologicalActivity
| Description | Talazoparib 8R,9S (BMN-673 8R,9S) is an enantiomer of Talazoparib, less active than Talazoparib on the inhibition of PARP1, with an IC50 of 144 nM. |
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| Related Catalog | Research Areas >>Cancer |
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| Target | PARP-1:144 nM (IC50) |
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| References | [1]. Wang B, et al. Discovery and Characterization of (8S,9R)-5-Fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-2,7,8,9-tetrahydro-3H-pyrido[4,3,2-de]phthalazin-3-one (BMN 673, Talazoparib), a Novel, Highly Potent, and Orally Efficacious Poly(ADP- |
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Chemical & Physical Properties
| Molecular Formula | C19H14F2N6O |
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| Molecular Weight | 380.35100 |
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| Exact Mass | 380.12000 |
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| PSA | 91.98000 |
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| LogP | 1.89830 |
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Synonyms
| (8R,9S)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-8,9-dihydro-2H-pyrido[4,3,2-de]phthalazin-3(7H)-one |
| BMN-673 8R,9S||BMN673 (8R,9S)|BMN 673 (8R,9S) |
| BMN 673 (8R,9S) |
| CS-1223 |
| BMN-673 (8R,9S) |
