Introduction：Basic information about CAS 14047-56-4|butanedioic acid,sodium, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | butanedioic acid,sodium |
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| CAS Number | 14047-56-4 | Molecular Weight | 141.07800 |
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| Density | / | Boiling Point | 158ºC at 760mmHg |
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| Molecular Formula | C4H6NaO4 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | butanedioic acid,sodium |
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| Synonym | More Synonyms |
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butanedioic acid,sodium BiologicalActivity
| Description | Succinic acid sodium is a potent and orally active anxiolytic agent. Succinic acid sodium shows inhibitory effects on colonic epithelial cell proliferation in vivo. Succinic acid sodium can down-regulate the expression of KCNMB1 (potassium channel subunit β1) and TET1 (ten‑eleven translocation 1). Succinic acid sodium can be used for gestational hypertension research[1][2][3]. |
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| Related Catalog | Research Areas >>Neurological DiseaseSignaling Pathways >>Membrane Transporter/Ion Channel >>Potassium Channel |
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| In Vivo | Succinic acid sodium (3.0 or 6.0 mg/kg, PO) increased the percentage of entries into open arms and of time spent on open arms[1]. succinic acid (3.0, 6.0, and 12.0 mg/kg, IP) caused significant increases in food intake during 5 min when compared with the vehicle[1]. Succinic acid sodium (100 mM) infused into rat colons significantly inhibits colonic cell proliferation and reduced crypt size[2]. |
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| References | [1]. Chen SW, Xin Q, Kong WX, Min L, Li JF. Anxiolytic-like effect of succinic acid in mice. Life Sci. 2003 Nov 7;73(25):3257-64. [2]. Inagaki A, et al. Inhibitory effect of succinic acid on epithelial cell proliferation of colonic mucosa in rats. J Nutr Sci Vitaminol (Tokyo). 2007 Aug;53(4):377-9. [3]. Zhou Y, et al. Fumaric acid and succinic acid treat gestational hypertension by downregulating the expression of KCNMB1 and TET1. Exp Ther Med. 2021 Oct;22(4):1072. |
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Chemical & Physical Properties
| Boiling Point | 158ºC at 760mmHg |
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| Molecular Formula | C4H6NaO4 |
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| Molecular Weight | 141.07800 |
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| Exact Mass | 141.01600 |
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| PSA | 74.60000 |
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| Vapour Pressure | 0.0165mmHg at 25°C |
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| InChIKey | DUMIASQJCCZABP-UHFFFAOYSA-N |
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| SMILES | O=C(O)CCC(=O)O.[Na] |
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Synonyms
| Butanedioic acid,sodium salt (1:) |
| EINECS 237-884-4 |
| Butanedioic acid,sodium salt |
