CAS 867062-95-1|Fmoc-NH-PEG3-CH2CH2COOH

Introduction:Basic information about CAS 867062-95-1|Fmoc-NH-PEG3-CH2CH2COOH, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameFmoc-NH-PEG3-CH2CH2COOH
CAS Number867062-95-1Molecular Weight443.490
Density1.2±0.1 g/cm3Boiling Point651.9±55.0 °C at 760 mmHg
Molecular FormulaC24H29NO7Melting Point/
MSDS/Flash Point348.0±31.5 °C

Names

Name1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13-tetraoxa-4-azahexadecan-16-oic acid
SynonymMore Synonyms

Fmoc-NH-PEG3-CH2CH2COOH BiologicalActivity

DescriptionFmoc-NH-PEG3-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>Antibody-drug Conjugate >>ADC Linker
Target

Cleavable

In VitroADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References

[1]. Kyoji TSUCHIKAMA, et al. Linkers for antibody drug conjugates. WO2018218004A1.

Chemical & Physical Properties

Density1.2±0.1 g/cm3
Boiling Point651.9±55.0 °C at 760 mmHg
Molecular FormulaC24H29NO7
Molecular Weight443.490
Flash Point348.0±31.5 °C
Exact Mass443.194397
PSA103.32000
LogP2.66
Vapour Pressure0.0±2.1 mmHg at 25°C
Index of Refraction1.562
InChIKeyCHIDDYZONKDHLG-UHFFFAOYSA-N
SMILESO=C(O)CCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc21
Storage condition2-8°C

Safety Information

HS Code2934999090

Customs

HS Code2934999090
Summary2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Synonyms

2,7,10,13-Tetraoxa-4-azahexadecan-16-oic acid, 1-(9H-fluoren-9-yl)-3-oxo-
2-[2-[2-(2-aminoethoxy)ethoxy]ethoxymethyl]-3-(9H-fluoren-9-ylmethoxy)-3-oxopropanoic acid
1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13-tetraoxa-4-azahexadecan-16-oic acid
Fmoc-12-Amino-4,7,10-Trioxadodecanoic Acid
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