Introduction：Basic information about CAS 214360-73-3|4-AMinophenylboronic acid pinacol ester, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 4-AMinophenylboronic acid pinacol ester |
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| CAS Number | 214360-73-3 | Molecular Weight | 219.09 |
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| Density | 1.1±0.1 g/cm3 | Boiling Point | 340.0±25.0 °C at 760 mmHg |
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| Molecular Formula | C12H18BNO2 | Melting Point | 165-169 °C(lit.) |
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| MSDS | / | Flash Point | 159.4±23.2 °C |
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Names
| Name | 4-Aminophenylboronic acid pinacol ester |
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| Synonym | More Synonyms |
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4-AMinophenylboronic acid pinacol ester BiologicalActivity
| Description | 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)aniline is a biochemical reagent that can be used as a biological material or organic compound for life science related research. |
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| Related Catalog | Research Areas >>Others |
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| In Vitro | 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaboran-2yl)aniline 是一种杂环结构单元。它已用于合成基于 3-氨基吲唑的多靶点受体具有抗癌活性的酪氨酸激酶 (RTK) 抑制剂和 roscovitine 衍生物，它们是细胞周期蛋白依赖性激酶 (CDK) 和酪蛋白激酶 1 (CK1) 的双重抑制剂。 |
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| References | [1]. Dai, Y., Hartandi, K., Ji, Z., et al al. Discovery of N-(4-(3-amino-1H-indazol-4-yl)phenyl)-N'-(2-fluoro-5-methylphenyl)urea (ABT-869), a 3-aminoindazole-based ORALLY ACTIVE MULTITARGED Receptor Tyrosine Kinase Inchibitorj. Chem.50 (7) 1584-1597 (2007). [2]. Paraiso, KHT, HAARBERG, He, Wood, E., ET Al.The HSP9 0 Inhibitor XL888 Overcomes Braf Inchibitor Resistance Mediated Through diverse mechanisms Clin. Cancer Res. 18(9) 2502-2514(2012). |
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Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
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| Boiling Point | 340.0±25.0 °C at 760 mmHg |
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| Melting Point | 165-169 °C(lit.) |
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| Molecular Formula | C12H18BNO2 |
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| Molecular Weight | 219.09 |
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| Flash Point | 159.4±23.2 °C |
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| Exact Mass | 219.143066 |
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| PSA | 44.48000 |
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| LogP | 2.14920 |
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| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
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| Index of Refraction | 1.517 |
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| InChIKey | ZANPJXNYBVVNSD-UHFFFAOYSA-N |
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| SMILES | CC1(C)OB(c2ccc(N)cc2)OC1(C)C |
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| Storage condition | Refrigerator (+4°C) |
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| Water Solubility | Insoluble |
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Safety Information
| Hazard Codes | Xi:Irritant |
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| Risk Phrases | R36/37/38 |
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| Safety Phrases | S26-S36-S37/39 |
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| WGK Germany | 3 |
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| HS Code | 2931900090 |
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Customs
| HS Code | 2931900090 |
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| Summary | 2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0% |
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Synonyms
| 4-AMINOBENZENEBORONIC ACID PINACOL ESTE |
| 4-AMINOPHENYLBORONIC ACID PINACOL CYCLIC ESTER |
| 4-METHYLPHENYLBORONIC ACID PINACOLATE |
| 4-AMINOPHENYLBORONIC ACID PINACOLATE |
| MFCD02258965 |
| 4-aminobenzeneboronic acid pinacol ester |
| 2-(4-Aminophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane |
| 4-Aminophenylboronic Acid Pinacol Ester |
| 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)aniline |
