CAS 547-81-9|16-Epiestriol
| Common Name | 16-Epiestriol | ||
|---|---|---|---|
| CAS Number | 547-81-9 | Molecular Weight | 288.38100 |
| Density | 1.255g/cm3 | Boiling Point | 469ºC at 760 mmHg |
| Molecular Formula | C18H24O3 | Melting Point | 289-291ºC |
| MSDS | USA | Flash Point | 220.8ºC |
Names
| Name | 16β-hydroxyestradiol |
|---|---|
| Synonym | More Synonyms |
16-Epiestriol BiologicalActivity
| Description | 16-Epiestriol is a metabolite of the endogenous estrogen estrone with antibacterial and anti-inflammatory effects[1][2][3]. |
|---|---|
| Related Catalog | Research Areas >>InfectionResearch Areas >>Inflammation/Immunology |
| References | [1]. Brinton LA, et al. Serum Estrogens and Estrogen Metabolites and Endometrial Cancer Risk among Postmenopausal Women. Cancer Epidemiol Biomarkers Prev. 2016 Jul;25(7):1081-9. [2]. Skariyachan S, et al. Natural epiestriol-16 act as potential lead molecule against prospective molecular targets of multidrug resistant Acinetobacter baumannii-Insight from in silico modelling and in vitro investigations. Infect Genet Evol. 2020 Aug;82:104314. [3]. Latman NS, et al. 16-epiestriol: an anti-inflammatory steroid without glycogenic activity. J Pharm Sci. 1994 Jun;83(6):874-7. |
Chemical & Physical Properties
| Density | 1.255g/cm3 |
|---|---|
| Boiling Point | 469ºC at 760 mmHg |
| Melting Point | 289-291ºC |
| Molecular Formula | C18H24O3 |
| Molecular Weight | 288.38100 |
| Flash Point | 220.8ºC |
| Exact Mass | 288.17300 |
| PSA | 60.69000 |
| LogP | 2.58000 |
| Index of Refraction | 1.624 |
| InChIKey | PROQIPRRNZUXQM-ZMSHIADSSA-N |
| SMILES | CC12CCC3c4ccc(O)cc4CCC3C1CC(O)C2O |
| Storage condition | -20°C |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
Articles8
More Articles| Associations of the fecal microbiome with urinary estrogens and estrogen metabolites in postmenopausal women. J. Clin. Endocrinol. Metab. 99(12) , 4632-40, (2014) The gut microbiota may influence the risk of breast cancer through effects on endogenous estrogens.The objective of the study was to investigate whether urinary estrogens and estrogen metabolites are ... | |
| Study of urinary steroid hormone disorders: difference between hepatocellular carcinoma in early stage and cirrhosis. Anal. Bioanal. Chem 406(18) , 4325-35, (2014) Hepatocellular carcinoma (HCC) is the fifth most common cancer in the world. Discovery of novel biomarkers for early HCC from other liver diseases such as cirrhosis is of great clinical benefit. In th... | |
| Comparison of metabolic ratios of urinary estrogens between benign and malignant thyroid tumors in postmenopausal women. BMC Clin. Pathol. 13 , 25, (2014) Estrogen metabolism may be associated with the pathophysiological development of papillary thyroid carcinoma (PTC).To evaluate the differential estrogen metabolism between benign and malignant PTCs, e... |
Synonyms
| 16-EPISTRIOL |
| Epiestriol |
| 16-epioestriol |
| Actriol |
| Estriol (3,16.β.,17.β.) |
| 16beta-hydroxyestradiol |
| 16b,17b-Estriol |
| EPIESTRIOL,16 |
| 16-EPIESTRIOL |
| Epioestriol |
| 16-Epiestratriol |
