Introduction:Basic information about CAS 151070-83-6|Immepip, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Immepip |
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| CAS Number | 151070-83-6 | Molecular Weight | 165.23500 |
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| Density | 1.084 g/cm3 | Boiling Point | 377.4ºC at 760 mmHg |
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| Molecular Formula | C9H15N3 | Melting Point | / |
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| MSDS | / | Flash Point | 182.1ºC |
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Names
| Name | 4-(1h-imidazol-4-ylmethyl)-piperidine |
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Immepip BiologicalActivity
| Description | Immepip is a H3 agonist. Immepip can reduce cortical histamine release. Immepip can be used for the research of neurological diseases[1]. |
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| Related Catalog | Signaling Pathways >>Immunology/Inflammation >>Histamine ReceptorResearch Areas >>Neurological DiseaseSignaling Pathways >>GPCR/G Protein >>Histamine Receptor |
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| In Vivo | Immepip (i.p.; 5, 10 mg/kg) 显著减少皮质组胺释放,但仅微弱地促进大鼠睡眠[1]。 Animal Model: Sprague-Dawley rats[1] Dosage: 5, 10 mg/kg Administration: Intraperitoneally Result: Significantly modulated brain histamine release and slight, albeit significant, decreased in sleep onset latency. |
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| References | [1]. Yves Lamberty, et al. H3 agonist immepip markedly reduces cortical histamine release, but only weakly promotes sleep in the rat. Pharmacol Res. 2003 Aug;48(2):193-8. |
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Chemical & Physical Properties
| Density | 1.084 g/cm3 |
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| Boiling Point | 377.4ºC at 760 mmHg |
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| Molecular Formula | C9H15N3 |
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| Molecular Weight | 165.23500 |
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| Flash Point | 182.1ºC |
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| Exact Mass | 165.12700 |
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| PSA | 40.71000 |
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| LogP | 1.28060 |
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| Vapour Pressure | 6.75E-06mmHg at 25°C |
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| Index of Refraction | 1.544 |
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| InChIKey | MCNGUYXRBCIGOV-UHFFFAOYSA-N |
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| SMILES | c1ncc(CC2CCNCC2)[nH]1 |
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