Introduction：Basic information about CAS 35542-01-9|5-methoxyuridine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 5-methoxyuridine |
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| CAS Number | 35542-01-9 | Molecular Weight | 274.23 |
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| Density | 1.65±0.1 g/cm3(Predicted) | Boiling Point | / |
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| Molecular Formula | C10H14N2O7 | Melting Point | / |
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| MSDS | ChineseUSA | Flash Point | / |
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Names
| Name | 5-methoxyuridine |
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| Synonym | More Synonyms |
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5-methoxyuridine BiologicalActivity
| Description | 5-Methoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/Analog |
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| References | [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. |
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Chemical & Physical Properties
| Density | 1.65±0.1 g/cm3(Predicted) |
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| Molecular Formula | C10H14N2O7 |
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| Molecular Weight | 274.23 |
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| Exact Mass | 274.08000 |
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| PSA | 134.01000 |
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| InChIKey | ZXIATBNUWJBBGT-JXOAFFINSA-N |
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| SMILES | COc1cn(C2OC(CO)C(O)C2O)c(=O)[nH]c1=O |
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| Storage condition | 2-8°C |
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Safety Information
| RIDADR | NONH for all modes of transport |
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| HS Code | 2934999090 |
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Customs
| HS Code | 2934999090 |
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| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Articles7
More Articles
| Codon recognition by tRNA molecules with a modified or unmodified uridine at the first position of the anticodon. Nucleic Acids Symp. Ser. 34 , 203-204, (1995) Effects of a single nucleoside modification at the first position of the anticodon of a transfer RNA molecule on its codon reading properties were investigated by use of a cell-free protein synthesis.... | |
| 5-methoxyuridine: a new minor constituent located in the first position of the anticodon of tRNAAla, tRNAThr, and tRNAVal from Bacillus subtilis. Nucleic Acids Res. 3 , 2851-2860, (1976) The sequences of the anticodon of tRNAAla, tRNAThr, and tRNAVal from Bacillus subtilis W 168 were N-G-C, N-G-U, and N-A-C, respectively. A new minor constituent, N, occupied the first position of the ... | |
| Bacillus subtilis tRNA(Pro) with the anticodon mo5UGG can recognize the codon CCC. Biochim. Biophys. Acta 1728 , 143-149, (2005) In Bacillus subtilis, four codons, CCU, CCC, CCA, and CCG, are used for proline. There exists, however, only one proline-specific tRNA having the anticodon mo(5)UGG. Here, we found that this tRNA(Pro)... | |
Synonyms
| 5-OMe-uridine |
| 5-METHOXYURIDINE |
