CAS 26166-37-0|Denudatine

Introduction：Basic information about CAS 26166-37-0|Denudatine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Denudatine BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	Denudatine
CAS Number	26166-37-0	Molecular Weight	343.503
Density	1.2±0.1 g/cm3	Boiling Point	488.2±45.0 °C at 760 mmHg
Molecular Formula	C₂₂H₃₃NO₂	Melting Point	248-249℃
MSDS	/	Flash Point	242.3±27.4 °C

Names

Name	denudatine
Synonym	More Synonyms

Denudatine BiologicalActivity

Description	Denudatine, is primarily isolated from plants of the genera Aconitum and Delphinium[1]. Denudatine has effects on action potential of ventricular fibers and inhibits arrhythmogenic action of aconitine[2].
Related Catalog	Research Areas >>Cardiovascular DiseaseSignaling Pathways >>Others >>Others
References	[1]. Nishiyama Y, et al. Synthesis of Cardiopetaline via a Wagner-Meerwein Rearrangement without Preactivation of the Pivotal Hydroxy Group. Org Lett. 2017 Nov 3;19(21):5833-5835. [2]. Liu TF, et al. Effects of denudatine on action potential of ventricular fibers and its inhibition on arrhythmogenic action of aconitine (author's transl). Zhongguo Yao Li Xue Bao. 1982 Mar;3(1):32-4.

Description

Denudatine, is primarily isolated from plants of the genera Aconitum and Delphinium[1]. Denudatine has effects on action potential of ventricular fibers and inhibits arrhythmogenic action of aconitine[2].

Related Catalog

Research Areas >>Cardiovascular DiseaseSignaling Pathways >>Others >>Others

References

[1]. Nishiyama Y, et al. Synthesis of Cardiopetaline via a Wagner-Meerwein Rearrangement without Preactivation of the Pivotal Hydroxy Group. Org Lett. 2017 Nov 3;19(21):5833-5835.

[2]. Liu TF, et al. Effects of denudatine on action potential of ventricular fibers and its inhibition on arrhythmogenic action of aconitine (author's transl). Zhongguo Yao Li Xue Bao. 1982 Mar;3(1):32-4.

Chemical & Physical Properties

Density	1.2±0.1 g/cm3
Boiling Point	488.2±45.0 °C at 760 mmHg
Melting Point	248-249℃
Molecular Formula	C₂₂H₃₃NO₂
Molecular Weight	343.503
Flash Point	242.3±27.4 °C
Exact Mass	343.251129
PSA	43.70000
LogP	3.07
Vapour Pressure	0.0±2.8 mmHg at 25°C
Index of Refraction	1.620
InChIKey	OVXLNQAYPUEDSI-ZAWREGRRSA-N
SMILES	C=C1C2CCC3(C1O)C1CC4C5(C)CCCC4(C1N(CC)C5)C3C2O
Storage condition	2-8C

Synonyms

(7α,11β,15β,20R)-21-Ethyl-4-methyl-7,20-cycloatid-16-ene-11,15-diol

(7α,11β,15β)-21-Ethyl-4-methyl-7,20-cycloatid-16-ene-11,15-diol

16,17-Didehydro-21-ethyl-4-methyl-7,20-cycloatidane-11-β,15-β-diol

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