Introduction：Basic information about CAS 53464-72-5|TMB-8, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | TMB-8 |
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| CAS Number | 53464-72-5 | Molecular Weight | 431.99 |
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| Density | 1.018g/cm3 | Boiling Point | 461.2ºC at 760mmHg |
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| Molecular Formula | C22H38ClNO5 | Melting Point | 94-97 °C(lit.) |
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| MSDS | ChineseUSA | Flash Point | 232.8ºC |
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Names
| Name | 8-(diethylamino)octyl 3,4,5-trimethoxybenzoate hydrochloride |
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| Synonym | More Synonyms |
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TMB-8 BiologicalActivity
| Description | TMB-8 is a novel Ca 2+ antagonist. TMB-8 may exert inhibitory effects in smooth muscle by blocking Ca 2+ release from intracellular bound stores. |
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| Related Catalog | Signaling Pathways >>Membrane Transporter/Ion Channel >>Calcium ChannelResearch Areas >>Neurological Disease |
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| References | [1]. Malagodi MH, et al. Pharmacological evaluation of a new Ca2+ antagonist, 8-(N,N-diethylamino)-octyl-3,4,5-trimethoxybenzoate hydrochloride (TMB-8): studies in smooth muscles. Eur J Pharmacol. 1974 Jun;27(1):25-33. |
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Chemical & Physical Properties
| Density | 1.018g/cm3 |
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| Boiling Point | 461.2ºC at 760mmHg |
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| Melting Point | 94-97 °C(lit.) |
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| Molecular Formula | C22H38ClNO5 |
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| Molecular Weight | 431.99 |
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| Flash Point | 232.8ºC |
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| Exact Mass | 431.24400 |
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| PSA | 57.23000 |
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| LogP | 5.35360 |
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| InChIKey | KFJZVXKPPQIYCG-UHFFFAOYSA-N |
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| SMILES | CCN(CC)CCCCCCCCOC(=O)c1cc(OC)c(OC)c(OC)c1.Cl |
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| Storage condition | -20°C Freezer |
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Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| Safety Phrases | S22-S24/25 |
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| RIDADR | NONH for all modes of transport |
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| WGK Germany | 3 |
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| HS Code | 2922509090 |
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Customs
| HS Code | 2922509090 |
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| Summary | 2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Synonyms
| MFCD00012502 |
| 8-(Diethylamino)octyl 3,4,5-trimethoxybenzoate hydrochloride |
| 8-(diethylamino)octyl 3,4,5-trimethoxybenzoate,hydrochloride |
| EINECS 258-574-5 |
