Introduction：Basic information about CAS 53696-74-5|Armillarisin A, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Armillarisin A |
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| CAS Number | 53696-74-5 | Molecular Weight | 234.205 |
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| Density | 1.5±0.1 g/cm3 | Boiling Point | 565.0±50.0 °C at 760 mmHg |
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| Molecular Formula | C12H10O5 | Melting Point | 250-255ºC |
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| MSDS | / | Flash Point | 227.2±23.6 °C |
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Names
| Name | 3-Acetyl-7-hydroxy-5-(hydroxymethyl)-2H-chromen-2-one |
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| Synonym | More Synonyms |
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Armillarisin A BiologicalActivity
| Description | Armillarisin A has the potential for the ulcerative colitis (UC) study. Armillarisin A increases IL-4 and lower IL-1β[1]. |
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| Related Catalog | Signaling Pathways >>Immunology/Inflammation >>Interleukin RelatedResearch Areas >>Inflammation/Immunology |
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| References | [1]. Ping Wu, et al. The Effects of Armillarisin A on Serum IL-1β and IL-4 and in Treating Ulcerative Colitis. Cell Biochem Biophys. 2015 May;72(1):103-6. |
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Chemical & Physical Properties
| Density | 1.5±0.1 g/cm3 |
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| Boiling Point | 565.0±50.0 °C at 760 mmHg |
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| Melting Point | 250-255ºC |
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| Molecular Formula | C12H10O5 |
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| Molecular Weight | 234.205 |
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| Flash Point | 227.2±23.6 °C |
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| Exact Mass | 234.052826 |
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| PSA | 87.74000 |
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| LogP | 0.13 |
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| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
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| Index of Refraction | 1.642 |
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| InChIKey | XVZWWNMZVZWQKU-UHFFFAOYSA-N |
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| SMILES | CC(=O)c1cc2c(CO)cc(O)cc2oc1=O |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- DJ2976500
- CHEMICAL NAME :
- 2H-1-Benzopyran-2-one, 3-acetyl-7-hydroxy-5-(hydroxymethyl)-
- CAS REGISTRY NUMBER :
- 53696-74-5
- LAST UPDATED :
- 199707
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C12-H10-O5
- MOLECULAR WEIGHT :
- 234.22
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- YHHPAL Yaoxue Xuebao. Acta Pharmaceutica Sinica. Pharmaceutical Journal. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 1953- Suspended 1966-78. Volume(issue)/page/year: 16,401,1981
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 980 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory depression
- REFERENCE :
- YHHPAL Yaoxue Xuebao. Acta Pharmaceutica Sinica. Pharmaceutical Journal. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 1953- Suspended 1966-78. Volume(issue)/page/year: 16,401,1981
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Safety Information
Customs
| HS Code | 2932209090 |
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| Summary | 2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| 3-Acetyl-5-hydroxylmethyl-7-hydroxycoumarin |
| 2H-1-Benzopyran-2-one, 3-acetyl-7-hydroxy-5-(hydroxymethyl)- |
| MFCD01662561 |
| 3-acetyl-7-hydroxy-5-(hydroxymethyl)chromen-2-one |
| 3-Acetyl-7-hydroxy-5-(hydroxymethyl)-2H-chromen-2-one |
| Armillarisin A |
