CAS 7568-93-6|phenylethanolamine
Introduction：Basic information about CAS 7568-93-6|phenylethanolamine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | phenylethanolamine | ||
|---|---|---|---|
| CAS Number | 7568-93-6 | Molecular Weight | 137.179 |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 286.9±13.0 °C at 760 mmHg |
| Molecular Formula | C8H11NO | Melting Point | 56-58 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | 151.4±10.5 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | phenylethanolamine |
|---|---|
| Synonym | More Synonyms |
phenylethanolamine BiologicalActivity
| Description | 2-Amino-1-phenylethanol is an analogue of noradrenaline. |
|---|---|
| Related Catalog | Natural Products >>OthersResearch Areas >>Others |
| Target | Human Endogenous Metabolite |
| References | [1]. Melandri S, et al. Shape of biomolecules by free jet microwave spectroscopy: 2-amino-1-phenylethanol and 2-methylamino-1-phenylethanol. J Phys Chem A. 2009 Jul 9;113(27):7769-73. |
Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 286.9±13.0 °C at 760 mmHg |
| Melting Point | 56-58 °C(lit.) |
| Molecular Formula | C8H11NO |
| Molecular Weight | 137.179 |
| Flash Point | 151.4±10.5 °C |
| Exact Mass | 137.084061 |
| PSA | 46.25000 |
| LogP | 0.82 |
| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
| Index of Refraction | 1.600 |
| InChIKey | ULSIYEODSMZIPX-UHFFFAOYSA-N |
| SMILES | NCC(O)c1ccccc1 |
| Stability | Stable. Incompatible with oxidizing agents, acids, acid chlorides, acid anhydrides. |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 250 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD691-490
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 686 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 47,96,1934
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1100 mg/kg
- TOXIC EFFECTS :
- Autonomic Nervous System - sympathomimetic
- REFERENCE :
- AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 153,161,1930
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 23 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 47,96,1934
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948 Volume(issue)/page/year: -,73,1948 *** REVIEWS *** TOXICOLOGY REVIEW CHREAY Chemical Reviews. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1924- Volume(issue)/page/year: 9,389,1931
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | DN5500000 |
Articles33
More Articles| A quantum dot based electrochemiluminescent immunosensor for the detection of pg level phenylethanolamine A using gold nanoparticles as substrates and electron transfer accelerators. Analyst 139(17) , 4365-72, (2014) This study reports the development of an electrochemiluminescent (ECL) immunosensor for ultrasensitive detection of phenylethanolamine A (PA) based on CdSe quantum dots (QDs) and gold nanoparticles (G... | |
| Development and validation of a sensitive method for simultaneous determination of eight β₂-agonists in pork by ultrasonic-assisted extraction and liquid chromatography/tandem mass spectrometry. J. Chromatogr. Sci. 53(1) , 104-11, (2014) A simple and sensitive ultrasonic-assisted extraction coupled with liquid chromatography-tandem quadrupole mass spectrometry was developed for the simultaneous determination of eight β2-agonists (i.e.... | |
| Simultaneous determination of plasma phenethylamine, phenylethanolamine, tyramine and octopamine by high-performance liquid chromatography using derivatization with fluorescamine. J. Chromatogr. A. 427(2) , 320-5, (1988) |
Synonyms
| Ethanol, 2- (phenylamino)- |
| β-Anilinoethanol |
| a-(Aminomethyl)benzyl alcohol |
| α-(Aminomethyl)benzyl alcohol |
| EINECS 231-469-1 |
| N-(β-hydroxy)ethylaniline |
| phenylethanolamine |
| Aniline, N-(β-hydroxyethyl)- |
| b-Hydroxyphenethylamine |
| Ethanol, 2-(phenylamino)- |
| β-Hydroxyphenethylamine |
| 2-(phenylamino)ethanol |
| N-(β-Hydroxyethyl)aniline |
| β-hydroxy-Phenethylamine |
| 2-Anilinoethanol |
| Benzenemethanol, α-(aminomethyl)- |
| dl-β-Phenyl-β-hydroxyethylamine |
| α-(Aminomethyl)benzenemethanol |
| β-hydroxy-β-phenyl-Ethylamine |
| (±)-phenylethanolamine |
| N-2-hydroxyethylaniline |
| 2-Amino-1-phenylethanol |
| MFCD00008137 |
