Introduction：Basic information about CAS 87075-18-1|Isolindleyin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Isolindleyin |
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| CAS Number | 87075-18-1 | Molecular Weight | 478.44600 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C23H26O11 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | Isolindleyin |
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| Synonym | More Synonyms |
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Isolindleyin BiologicalActivity
| Description | Isolindleyin, a butyrophenone, is a tyrosinase inhibitor, with a Kd of 54.8 μM for human tyrosinase. Isolindleyin exhibits anti-inflammatory, analgesic and anti-melanogenic activities[1]. |
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| Related Catalog | Research Areas >>Inflammation/ImmunologySignaling Pathways >>Metabolic Enzyme/Protease >>Tyrosinase |
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| Target | Kd: 54.8 μM (human tyrosinase)[1] |
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| In Vitro | Isolindley (1-500 μM; 7 days) suppresses melanin synthesis in human epidermal melanocytes[1]. |
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| References | [1]. Lee JY, et, al. Isolindleyin exerts anti-melanogenic effects in human epidermal melanocytes via direct binding to tyrosinase. Biochem Biophys Res Commun. 2021 Jan 1;534:802-807. |
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Chemical & Physical Properties
| Molecular Formula | C23H26O11 |
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| Molecular Weight | 478.44600 |
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| Exact Mass | 478.14800 |
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| PSA | 183.21000 |
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| LogP | 0.36840 |
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| InChIKey | KHUVRRVIZOSFTI-UHFFFAOYSA-N |
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| SMILES | CC(=O)CCc1ccc(OC2OC(CO)C(O)C(O)C2OC(=O)c2cc(O)c(O)c(O)c2)cc1 |
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Synonyms
| 4-(4'-hydroxyphenyl)-2-butanone 4'-O-β-D-(2-O-galloyl)-glycopyranoside |
