CAS 20501-56-8|talatisamine

Introduction：Basic information about CAS 20501-56-8|talatisamine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. talatisamine BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	talatisamine
CAS Number	20501-56-8	Molecular Weight	421.570
Density	1.3±0.1 g/cm3	Boiling Point	533.9±50.0 °C at 760 mmHg
Molecular Formula	C₂₄H₃₉NO₅	Melting Point	151-152℃
MSDS	/	Flash Point	276.7±30.1 °C

Names

Name	talatisamine
Synonym	More Synonyms

talatisamine BiologicalActivity

Description	Talatisamine, a aconitum alkaloid，is specific K+ channel blocker. Talatisamine attenuates beta-amyloid oligomers induced neurotoxicity in cultured cortical neurons[1].
Related Catalog	Research Areas >>Neurological DiseaseSignaling Pathways >>Membrane Transporter/Ion Channel >>Potassium Channel
References	[1]. Wang Y, et al. The newly identified K+ channel blocker talatisamine attenuates beta-amyloid oligomers induced neurotoxicity in cultured cortical neurons. Neurosci Lett. 2012 Jun 19;518(2):122-7.

Chemical & Physical Properties

Density	1.3±0.1 g/cm3
Boiling Point	533.9±50.0 °C at 760 mmHg
Melting Point	151-152℃
Molecular Formula	C₂₄H₃₉NO₅
Molecular Weight	421.570
Flash Point	276.7±30.1 °C
Exact Mass	421.282837
PSA	71.39000
LogP	-0.50
Vapour Pressure	0.0±3.2 mmHg at 25°C
Index of Refraction	1.588
InChIKey	BDCURAWBZJMFIK-FLDLCTCNSA-N
SMILES	CCN1CC2(COC)CCC(OC)C34C5CC6C(OC)CC(O)(C(CC23)C14)C5C6O
Storage condition	2-8C

Synonyms

talatizamine

Talatisamine

(1α,14α,16β)-20-Ethyl-1,16-dimethoxy-4-(methoxymethyl)aconitane-8,14-diol

20-Ethyl-1-α,16-β-dimethoxy-4-(methoxymethyl)aconitane-8,14-α-diol

Aconitane-8,14-diol, 20-ethyl-1,16-dimethoxy-4-(methoxymethyl)-, (1α,4β,14α,16β)-

(16S)-20-ethyl-1α,16-dimethoxy-4-methoxymethyl-aconitane-8,14α-diol

(16S)-20-Aethyl-1α,16-dimethoxy-4-methoxymethyl-aconitan-8,14α-diol

Aconitane-8,14-diol, 20-ethyl-1,16-dimethoxy-4-(methoxymethyl)-, (1α,14α,16β)-

(1α,4β,14α,16β)-20-Ethyl-1,16-dimethoxy-4-(methoxymethyl)aconitane-8,14-diol

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