CAS 5416-71-7|3,4-Dimethoxychalcone

Introduction:Basic information about CAS 5416-71-7|3,4-Dimethoxychalcone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name3,4-Dimethoxychalcone
CAS Number5416-71-7Molecular Weight268.31
Density1.128g/cm3Boiling Point421.8ºC at 760mmHg
Molecular FormulaC17H16O3Melting Point88ºC
MSDS/Flash Point200.7ºC

Names

Name3,4-dimethoxychalcone
SynonymMore Synonyms

3,4-Dimethoxychalcone BiologicalActivity

Description3,4-Dimethoxychalcone is a Caloric restriction mimetics (CRMs). 3,4-Dimethoxychalcone induces the deacetylation of cytoplasmic proteins and stimulates autophagy flux. 3,4-Dimethoxychalcone can be used for cardiac and cancer diseases research[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>Autophagy >>AutophagySignaling Pathways >>Anti-infection >>Bacterial
References

[1]. Okolo EN, et al. New chalcone derivatives as potential antimicrobial and antioxidant agent. Sci Rep. 2021 Nov 5;11(1):21781.  

[2]. Chen G, et al. 3,4-Dimethoxychalcone induces autophagy through activation of the transcription factors TFE3 and TFEB. EMBO Mol Med. 2019 Nov 7;11(11):e10469.  

Chemical & Physical Properties

Density1.128g/cm3
Boiling Point421.8ºC at 760mmHg
Melting Point88ºC
Molecular FormulaC17H16O3
Molecular Weight268.31
Flash Point200.7ºC
Exact Mass268.11000
PSA35.53000
LogP3.59990

Synonyms

1-phenyl-3-(3,4-dimethoxyphenyl)-2-propen-1-one
3,4-dimethoxybenzylideneacetophenone
(E)-3-(3,4-DIMETHOXYPHENYL)-1-PHENYLPROP-2-EN-1-ONE
3-(3,4-dimethoxy-phenyl)-1-propenone
3,4-Dimethoxy-chalkon
DIMETHOXYCHALCONE,3,4
3,4-dimethoxy-chalcone
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