CAS 149-44-0|Sodium hydroxymethanesulfinate

CHEMICAL IDENTIFICATION

RTECS NUMBER :

PB0380000

CHEMICAL NAME :

Methanesulfinic acid, hydroxy-, monosodium salt

CAS REGISTRY NUMBER :

149-44-0

LAST UPDATED :

199701

DATA ITEMS CITED :

7

MOLECULAR FORMULA :

C-H4-O3-S.Na

MOLECULAR WEIGHT :

119.10

WISWESSER LINE NOTATION :

Q1SQO &-NA-

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

>2 gm/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

YKYUA6 Yakkyoku. Pharmacy. (Nanzando, 4-1-11, Yushima, Bunkyo-ku, Tokyo, Japan) V.1- 1950- Volume(issue)/page/year: 31,959,1980

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

>2 gm/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

YKYUA6 Yakkyoku. Pharmacy. (Nanzando, 4-1-11, Yushima, Bunkyo-ku, Tokyo, Japan) V.1- 1950- Volume(issue)/page/year: 31,959,1980

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

4 gm/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

YKYUA6 Yakkyoku. Pharmacy. (Nanzando, 4-1-11, Yushima, Bunkyo-ku, Tokyo, Japan) V.1- 1950- Volume(issue)/page/year: 31,959,1980 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83726 No. of Facilities: 5560 (estimated) No. of Industries: 46 No. of Occupations: 29 No. of Employees: 21898 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83726 No. of Facilities: 2998 (estimated) No. of Industries: 10 No. of Occupations: 37 No. of Employees: 239465 (estimated) No. of Female Employees: 187432 (estimated)

Arch. Biochem. Biophys. 367(2) , 289-96, (1999)

Sodium hydroxymethanesulfinate, (HOCH2SO2Na, HMS) is relatively stable in aqueous alkaline environments, but rapidly decomposes in acidic medium to give a variety of products that include sulfur dioxi...