CAS 842-15-9|7-AMINO-1,3-NAPHTHALENEDISULFONIC ACID MONOPOTASSIUM SALT

Introduction:Basic information about CAS 842-15-9|7-AMINO-1,3-NAPHTHALENEDISULFONIC ACID MONOPOTASSIUM SALT, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name7-AMINO-1,3-NAPHTHALENEDISULFONIC ACID MONOPOTASSIUM SALT
CAS Number842-15-9Molecular Weight341.40200
Density0.881 g/mL at 25 °C(lit.)Boiling Point159-161 °C(lit.)
Molecular FormulaC10H8KNO6S2Melting Point−69 °C(lit.)
MSDS/Flash Point107 °F

Names

Name2-Naphthylamine-6,8-Disulfonic Acid Monopotassium Salt
SynonymMore Synonyms

BiologicalActivity

Description2-Naphthylamine-6,8-disulfonic acid potassium is chemical that can be used for preparing dyestuff, medicine, agricultural chemicals etc[1].
Related CatalogSignaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology
In Vitro2-Naphthylamine-6,8-disulfonic acid potassium (compound 20) can inhibit human immunodeficiency virus HIV-1 and HIV-2 by 11% and 13.6% at a concentration of 1369 μM, respectively[1]. 2-Naphthylamine-6,8-disulfonic acid potassium (ANDS) can directly analyze polyglycolic pyrophosphate-linked oligosaccharides in cell cultures and tissues[3]. Guidelines (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs).Labeling oligosaccharides[3]: 1. Prepared 0.15 M ANDS with 15% (v/v) acetic acid. 2. Prepare 1M solution of sodium cyanoborohydride in dimethyl sulfoxide (DMSO). 3. Add 5 μL ANDS reagent (1 μL if sample is below 200 pmol) to the sample. 4. Add 5 μL sodium cyanoborohydride solution (1 μL if sample is below 200 pmol) to the sample. 5. After mixing, the reaction was briefly centrifuged and allowed to dry for 18 hours at 37 °C.
References

[1]. G T Tan, et al. Potential anti-AIDS naphthalenesulfonic acid derivatives. Synthesis and inhibition of HIV-1 induced cytopathogenesis and HIV-1 and HIV-2 reverse transcriptase activities. J Med Chem. 1992 Dec 25;35(26):4846-53.

[2]. K B Lee, et al. A new method for sequencing linear oligosaccharides on gels using charged, fluorescent conjugates. Carbohydr Res. 1991 Jul 18;214(1):155-68.

[3]. Ningguo Gao, et al. Fluorophore-assisted carbohydrate electrophoresis: a sensitive and accurate method for the direct analysis of dolichol pyrophosphate-linked oligosaccharides in cell cultures and tissues. Methods. 2005 Apr;35(4):323-7.

[4]. Preparation method of 2-naphthylamine 6,8 disulfonic acid. CN102295585A.

Chemical & Physical Properties

Density0.881 g/mL at 25 °C(lit.)
Boiling Point159-161 °C(lit.)
Melting Point−69 °C(lit.)
Molecular FormulaC10H8KNO6S2
Molecular Weight341.40200
Flash Point107 °F
Exact Mass340.94300
PSA154.35000
LogP3.31560
Index of Refractionn20/D 1.425(lit.)

Safety Information

Hazard CodesXi: Irritant;
Risk PhrasesR36/37/38
Safety PhrasesS22-S24/25
WGK Germany3
HS Code2921450090

Customs

HS Code2921450090
Summary2921450090 1-naphthylamine (α-naphthylamine), 2-naphthylamine (β-naphthylamine) and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Synonyms

7-amino-1,3-naphthalenedisulfonic acid monopotassium salt
EINECS 212-669-8
MFCD00064177
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