Introduction：Basic information about CAS 2140-72-9|2′-O-methylcytidine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2′-O-methylcytidine |
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| CAS Number | 2140-72-9 | Molecular Weight | 257.243 |
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| Density | 1.7±0.1 g/cm3 | Boiling Point | 506.0±60.0 °C at 760 mmHg |
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| Molecular Formula | C10H15N3O5 | Melting Point | 252-253ºC |
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| MSDS | ChineseUSA | Flash Point | 259.8±32.9 °C |
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Names
| Name | 2'-O-methylcytidine |
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| Synonym | More Synonyms |
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2′-O-methylcytidine BiologicalActivity
| Description | 2'-O-Methylcytidine is a 2'-substituted nucleoside as a inhibitor of HCV replication. 2'-O-Methylcytidine inhibits RNA-dependent RNA polymerase (NS5B)-catalyzed RNA synthesis in vitro, in a manner that is competitive with substrate nucleoside triphosphate[1]. |
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| Related Catalog | Signaling Pathways >>Anti-infection >>HCVResearch Areas >>Infection |
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| References | [1]. Steven S Carroll, et al. Inhibition of hepatitis C virus RNA replication by 2'-modified nucleoside analogs. J Biol Chem. 2003 Apr 4;278(14):11979-84 |
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Chemical & Physical Properties
| Density | 1.7±0.1 g/cm3 |
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| Boiling Point | 506.0±60.0 °C at 760 mmHg |
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| Melting Point | 252-253ºC |
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| Molecular Formula | C10H15N3O5 |
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| Molecular Weight | 257.243 |
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| Flash Point | 259.8±32.9 °C |
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| Exact Mass | 257.101166 |
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| PSA | 119.83000 |
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| LogP | -1.09 |
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| Vapour Pressure | 0.0±3.0 mmHg at 25°C |
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| Index of Refraction | 1.677 |
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| InChIKey | RFCQJGFZUQFYRF-ZOQUXTDFSA-N |
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| SMILES | COC1C(O)C(CO)OC1n1ccc(N)nc1=O |
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| Storage condition | −20°C |
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Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| Hazard Codes | Xi |
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| Risk Phrases | R36/37/38 |
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| Safety Phrases | 26-36 |
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| RIDADR | NONH for all modes of transport |
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| WGK Germany | 3 |
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| HS Code | 2934999090 |
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Customs
| HS Code | 2934999090 |
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| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| 2'-OMe Cytidine |
| 4-amino-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]pyrimidin-2-one |
| 2'-OMeCytidine |
| 2'-O-Methyl-D-cytidine |
| 2’-O-Methyl Cytidine |
| O2'-methylcytidine |
| 4-Amino-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydro-2-furanyl]-2(1H)-pyrimidinone |
| 4-azanyl-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxy-oxolan-2-yl]pyrimidin-2-one |
| 4-Amino-1-(2-O-methyl-β-D-ribofuranosyl)pyrimidin-2(1H)-on |
| Cytidine, 2'-O-methyl- |
| 2'-OMe-C |
| 2'-O-methyl-2'-deoxy-cytidine |
| 2′-O-methylcytidine |
| MFCD00056067 |
| 2'-O-Methylcytidine |
| 2'-O-Methylcytidine |
| 2'-O-methyl-cytidine |
| 4-amino-1-[(2R,3R,4R,5R)-4-hydroxy-3-methoxy-5-methylol-tetrahydrofuran-2-yl]pyrimidin-2-one |
| 2'-O-(TERT-BUTYLDIMETHYLSILYL)-6A-HYDROXY-7-EPI-PACLITAXEL |
