CAS 55486-00-5|Decylubiquinone

Introduction：Basic information about CAS 55486-00-5|Decylubiquinone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Decylubiquinone BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	Decylubiquinone
CAS Number	55486-00-5	Molecular Weight	322.43900
Density	1.02g/cm3	Boiling Point	452.9ºC at 760 mmHg
Molecular Formula	C₁₉H₃₀O₄	Melting Point	/
MSDS	/	Flash Point	196.2ºC

Names

Name	6-decylubiquinone
Synonym	More Synonyms

Decylubiquinone BiologicalActivity

Description	Decylubiquinone is an analog of ubiquinone (coenzyme Q10). Decylubiquinone blocks reactive oxygen species (ROS) production in response to glutathione depletion and inhibits activation of the mitochondrial permeability transition[1].
Related Catalog	Research Areas >>CancerResearch Areas >>Neurological Disease
In Vitro	Decylubiquinone (dUb; 10 μm for 6 hours) exerts its effects on ROS by either inhibition of ROS production by cytochrome bc1 or that it scavenged ROS produced[1]. Decylubiquinone inhibits both the dichlorofluorescein (DCF) fluorescence increase resulting from H2O2 treatment and the DCF fluorescence increase resulting after glutathione (GSH) depletion using diethylmaleate mitochondrially generated ROS)[1]. Cell Viability Assay[1] Cell Line: HL60 cells transfected with bcl-2 (bcl-2) (HL60 B cells) Concentration: 10 μM Incubation Time: 6 hours Result: Attenuated the ROS increase in HL60 (B) cells.
References	[1]. Jeffrey S Armstrong, et al. The Coenzyme Q10 analog decylubiquinone inhibits the redox-activated mitochondrial permeability transition: role of mitcohondrial [correction mitochondrial] complex III. J Biol Chem. 2003 Dec 5;278(49):49079-84.

Chemical & Physical Properties

Density	1.02g/cm3
Boiling Point	452.9ºC at 760 mmHg
Molecular Formula	C₁₉H₃₀O₄
Molecular Weight	322.43900
Flash Point	196.2ºC
Exact Mass	322.21400
PSA	52.60000
LogP	4.48990
Index of Refraction	1.487
InChIKey	VMEGFMNVSYVVOM-UHFFFAOYSA-N
SMILES	CCCCCCCCCCC1=C(C)C(=O)C(OC)=C(OC)C1=O

Safety Information

Hazard Codes	Xi
Risk Phrases	36/37/38
Safety Phrases	26-36

Synonyms

2-decyl-5,6-dimethoxy-3-methyl-1,4-benzoquinone

decylubiquinone

2,3-dimethoxy-5-methyl-6-(n-decyl)-1,4-benzoquinone

2,3-Dmdb

2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione

decylbenzylquinone

MFCD00083306

6-Decylubiquinone

2,3-Dimethoxy-5-methyl-6-decyl-1,4-benzoquinone

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