CAS 5306-85-4|1,4:3,6-Dianhydro-2,5-di-O-methyl-D-glucitol

Introduction：Basic information about CAS 5306-85-4|1,4:3,6-Dianhydro-2,5-di-O-methyl-D-glucitol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Customs
6. Synonyms

Common Name	1,4:3,6-Dianhydro-2,5-di-O-methyl-D-glucitol
CAS Number	5306-85-4	Molecular Weight	174.19
Density	1.2±0.1 g/cm3	Boiling Point	236.4±40.0 °C at 760 mmHg
Molecular Formula	C₈H₁₄O₄	Melting Point	-70°C
MSDS	/	Flash Point	108.3±0.0 °C

Names

Name	Isosorbide Dimethyl Ether
Synonym	More Synonyms

BiologicalActivity

Description	Isosorbide dimethyl ether is a biobased high boiling green solvent. Isosorbide dimethyl ether can be used for sustainable ultrafiltration and microfiltration membrane preparation. Isosorbide dimethyl ether can be used as an excipient, such as solvent, penetration aid. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2].
Related Catalog	Research Areas >>OthersSignaling Pathways >>Others >>Others
References	[1]. Russo F, et al. Dimethyl isosorbide as a green solvent for sustainable ultrafiltration and microfiltration membrane preparation[J]. ACS Sustainable Chemistry & Engineering, 2019, 8(1): 659-668. [2]. Elder DP, et al. Pharmaceutical excipients - quality, regulatory and biopharmaceutical considerations. Eur J Pharm Sci. 2016 May 25;87:88-99.

Description

Isosorbide dimethyl ether is a biobased high boiling green solvent. Isosorbide dimethyl ether can be used for sustainable ultrafiltration and microfiltration membrane preparation. Isosorbide dimethyl ether can be used as an excipient, such as solvent, penetration aid. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2].

Related Catalog

Research Areas >>OthersSignaling Pathways >>Others >>Others

References

[1]. Russo F, et al. Dimethyl isosorbide as a green solvent for sustainable ultrafiltration and microfiltration membrane preparation[J]. ACS Sustainable Chemistry & Engineering, 2019, 8(1): 659-668.

[2]. Elder DP, et al. Pharmaceutical excipients - quality, regulatory and biopharmaceutical considerations. Eur J Pharm Sci. 2016 May 25;87:88-99.

Chemical & Physical Properties

Density	1.2±0.1 g/cm3
Boiling Point	236.4±40.0 °C at 760 mmHg
Melting Point	-70°C
Molecular Formula	C₈H₁₄O₄
Molecular Weight	174.19
Flash Point	108.3±0.0 °C
Exact Mass	174.089203
PSA	36.92000
LogP	-0.65
Vapour Pressure	0.1±0.5 mmHg at 25°C
Index of Refraction	1.466
InChIKey	MEJYDZQQVZJMPP-ULAWRXDQSA-N
SMILES	COC1COC2C(OC)COC12

Safety Information

Safety Phrases	S23-S24/25
WGK Germany	3
HS Code	2932999099

Customs

HS Code	2932999099
Summary	2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Synonyms

D-Glucitol, 1,4:3,6-dianhydro-2,5-di-O-methyl-

MFCD00064828

EINECS 226-159-8

(3S,3aR,6R,6aR)-3,6-dimethoxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan

Glucitol, 1,4:3,6-dianhydro-2,5-di-O-methyl-, D-

Isosorbide DiMethyl Ether

D-Glucitol, 1,4:3,6-dianhydro-2,5-di-O-methyl

1,4:3,6-Dianhydro-2,5-di-O-methyl-D-glucitol

(3R,3aR,6S,6aR)-3,6-Dimethoxyhexahydrofuro[3,2-b]furan

Recommended......