CAS 996-19-0|Aminoguanidine hemisulfate
| Common Name | Aminoguanidine hemisulfate | ||
|---|---|---|---|
| CAS Number | 996-19-0 | Molecular Weight | 123.13 |
| Density | / | Boiling Point | 261.4ºC at 760mmHg |
| Molecular Formula | CH6N4.1/2H2O4 | Melting Point | 200 °C |
| MSDS | USA | Flash Point | 111.9ºC |
Names
| Name | Aminoguanidine Hemisulfate |
|---|---|
| Synonym | More Synonyms |
Aminoguanidine hemisulfate BiologicalActivity
| Description | Aminoguanidine hemisulfate is an inhibitor of NOS and ROS. Aminoguanidine hemisulfate abolishes ANE-induced ROS production in vitro. Aminoguanidine hemisulfate is used for cancer research[1]. |
|---|---|
| Related Catalog | Research Areas >>Cancer |
| Target | IC50: ROS, NOS[1] |
| References | [1]. Po-Li Wei, et al. Areca nut extract (ANE) inhibits the progression of hepatocellular carcinoma cells via activation of ROS production and activation of autophagy. Int J Med Sci. 2021 Aug 9;18(15):3452-3462. [2]. You-Ting Zhu, et al. Effects of L-arginine on Nitric Oxide Synthesis and Larval Metamorphosis of Mytilus coruscus. Genes (Basel). 2023 Feb 9;14(2):450. |
Chemical & Physical Properties
| Boiling Point | 261.4ºC at 760mmHg |
|---|---|
| Melting Point | 200 °C |
| Molecular Formula | CH6N4.1/2H2O4 |
| Molecular Weight | 123.13 |
| Flash Point | 111.9ºC |
| Exact Mass | 246.085876 |
| PSA | 258.82000 |
| LogP | 0.89680 |
| InChIKey | VKGQPUZNCZPZKI-UHFFFAOYSA-N |
| SMILES | NN=C(N)N.NN=C(N)N.O=S(=O)(O)O |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Safety Phrases | S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 2 |
| HS Code | 2925290090 |
Customs
| HS Code | 2928000090 |
|---|---|
| Summary | 2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0% |
Articles4
More Articles| Modulation of cytochrome P450 2A5 activity by lipopolysaccharide: low-dose effects and non-monotonic dose-response relationship. PLoS ONE 10(1) , e0117842, (2015) Mouse cytochrome P450 (CYP) 2A5 is induced by inflammatory conditions and infectious diseases that down-regulate the expression and activity of most other CYP isoforms. Enhanced oxidative stress and n... | |
| A simple assay for mammalian spermine oxidase: a polyamine catabolic enzyme implicated in drug response and disease. Methods Mol. Biol. 720 , 173-81, (2011) Spermine oxidase (SMO), the most recently characterized polyamine metabolic enzyme, catalyzes the direct back-conversion of spermine to spermidine in an FAD-dependent reaction that also yields the byp... | |
| Effects of nitric oxide on ovulation and ovarian steroidogenesis and prostaglandin production in the rabbit. Endocrinology 138 , 3630-7, (1997) Evidence supports the involvement of nitric oxide (NO) in ovarian physiology. The present study was undertaken to investigate the role of the NO/NO synthase (NOS) systems in ovulation, oocyte maturati... |
Synonyms
| EINECS 213-628-7 |
| Carbonohydrazonic diamide, sulfate (2:1) |
| Aminoguanidine hemisulfate |
| Bis(carbamimidoylhydrazinium) sulfate |
| MFCD00035665 |
| Carbonohydrazonic diamide sulfate (2:1) |
