Introduction:Basic information about CAS 99-11-6|Citrazinic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Citrazinic acid |
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| CAS Number | 99-11-6 | Molecular Weight | 155.11 |
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| Density | 1.7±0.1 g/cm3 | Boiling Point | 630.3±55.0 °C at 760 mmHg |
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| Molecular Formula | C6H5NO4 | Melting Point | >300 °C(lit.) |
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| MSDS | ChineseUSA | Flash Point | 335.0±31.5 °C |
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| Symbol | GHS07 | Signal Word | Warning |
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Names
| Name | Citrazinic acid |
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| Synonym | More Synonyms |
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Citrazinic acid BiologicalActivity
| Description | Citrazinic acid is a weakly fluorescent compound whose optical properties are dependent on aggregation states and chemical environment. Citrazinic acid strongly tends to form dimers at high concentrations[1]. |
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| Related Catalog | Research Areas >>Others |
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| References | [1]. Stagi L, et al. Anomalous Optical Properties of Citrazinic Acid under Extreme pH Conditions. ACS Omega. 2020 May 5;5(19):10958-10964. |
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Chemical & Physical Properties
| Density | 1.7±0.1 g/cm3 |
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| Boiling Point | 630.3±55.0 °C at 760 mmHg |
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| Melting Point | >300 °C(lit.) |
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| Molecular Formula | C6H5NO4 |
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| Molecular Weight | 155.11 |
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| Flash Point | 335.0±31.5 °C |
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| Exact Mass | 155.021851 |
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| PSA | 90.65000 |
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| LogP | -1.50 |
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| Vapour Pressure | 0.0±1.9 mmHg at 25°C |
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| Index of Refraction | 1.686 |
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| InChIKey | CSGQJHQYWJLPKY-UHFFFAOYSA-N |
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| SMILES | O=C(O)c1cc(O)[nH]c(=O)c1 |
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| Water Solubility | practically insoluble |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- NS1400000
- CHEMICAL NAME :
- Isonicotinic acid, 2,6-dihydroxy-
- CAS REGISTRY NUMBER :
- 99-11-6
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C6-H5-N-O4
- MOLECULAR WEIGHT :
- 155.12
- WISWESSER LINE NOTATION :
- T6NJ BQ DVQ FQ
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >3200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- KODAK* Kodak Company Reports. (343 State St., Rochester, NY 14650) Volume(issue)/page/year: 21MAY1971
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 800 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- KODAK* Kodak Company Reports. (343 State St., Rochester, NY 14650) Volume(issue)/page/year: 21MAY1971
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- >20 mL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- KODAK* Kodak Company Reports. (343 State St., Rochester, NY 14650) Volume(issue)/page/year: 21MAY1971 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - T1498 No. of Facilities: 43 (estimated) No. of Industries: 2 No. of Occupations: 3 No. of Employees: 255 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - T1498 No. of Facilities: 6 (estimated) No. of Industries: 2 No. of Occupations: 1 No. of Employees: 34 (estimated) No. of Female Employees: 3 (estimated)
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Safety Information
| Symbol | GHS07 |
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| Signal Word | Warning |
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| Hazard Statements | H315-H319-H335 |
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| Precautionary Statements | P261-P305 + P351 + P338 |
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| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
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| Hazard Codes | Xi:Irritant; |
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| Risk Phrases | R36/37/38 |
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| Safety Phrases | S26-S36-S36/37/39-S22 |
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| RIDADR | NONH for all modes of transport |
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| WGK Germany | 1 |
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| RTECS | NS1400000 |
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| HS Code | 29333999 |
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Customs
| HS Code | 2933399090 |
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| Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Articles2
More Articles
| 6,6'-Dibromo-4,4'-di(hexoxymethyl)-2,2'- bipyridine: a new solubilizing building block for macromolecular and supramolecular applications. J. Org. Chem. 71(12) , 4696-9, (2006) Although brominated bipyridines and terpyridines are highly desirable synthetic building blocks for both ligand design and macro- or supramolecular applications, few such synthetic precursors have bee... | |
| Synthesis and antimicrobial activity of some new pyrimidinone and oxazinone derivatives fused with thiophene rings using 2-chloro-6-ethoxy-4-acetylpyridine as starting material. Molecules 17(11) , 13642-55, (2012) A series of pyridines, pyrimidinones, oxazinones and their derivatives were synthesized as antimicrobial agents using citrazinic acid (2,6-dihydroxyisonicotinic acid) as a starting material. α,β-Unsat... | |
Synonyms
| 2-hydroxy-6-oxo-1H-pyridine-4-carboxylic acid |
| 4-Pyridinecarboxylic acid, 1,2-dihydro-6-hydroxy-2-oxo- |
| EINECS 202-731-2 |
| 6-Hydroxy-4-carboxy-2-pyridone |
| MFCD00006274 |
| 2,6-Dihydroxy-isonicotinic acid |
| 1,2-Dihydro-6-hydroxy-2-oxo-4-pyridinecarboxylic Acid |
| 6-hydroxy-2-oxo-1,2-dihydropyridine-4-carboxylic acid |
| Citrazinic acid |
| 6-Hydroxy-2-oxo-1,2-dihydro-4-pyridinecarboxylic acid |