Introduction：Basic information about CAS 549-92-8|Sempervirine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Sempervirine |
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| CAS Number | 549-92-8 | Molecular Weight | 331.32500 |
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| Density | 1.28g/cm3 | Boiling Point | 591.6ºC at 760mmHg |
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| Molecular Formula | C19H16N2 | Melting Point | 271ºC |
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| MSDS | / | Flash Point | 311.6ºC |
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Names
| Name | sempervirine nitrate |
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| Synonym | More Synonyms |
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Sempervirine BiologicalActivity
| Description | Sempervirine is an indole alkaloid isolated from Gelsemium sempervirens with anti-tumor activities. Sempervirine is against sempervirine-sensitive tumor cells with EC50 values of 2.7 μM, 1.77 μM, and 1.96 μM for Raji, MDA-MB-231 and HeLa cells, respectively[2]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Others >>Others |
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| References | [1]. Noriyuki Kogure, et al. Total synthesis and full NMR assignment of ourouparine, a yohimbane-type indole alkaloid isolated from Gelsemium sempervirens. Journal of Natural Medicines volume |
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Chemical & Physical Properties
| Density | 1.28g/cm3 |
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| Boiling Point | 591.6ºC at 760mmHg |
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| Melting Point | 271ºC |
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| Molecular Formula | C19H16N2 |
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| Molecular Weight | 331.32500 |
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| Flash Point | 311.6ºC |
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| Exact Mass | 331.09600 |
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| PSA | 88.77000 |
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| LogP | 4.49710 |
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| InChIKey | UQVUEULZDJRMJR-UHFFFAOYSA-N |
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| SMILES | c1ccc2c3ccn4cc5c(cc4c-3nc2c1)CCCC5 |
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Safety Information
| Risk Phrases | 23/24/25 |
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| Safety Phrases | 22-36/37/39 |
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Synonyms
| sempervirine |
| yohimba-2,5,14,20-tetraene |
| Sempervirin |
