Introduction：Basic information about CAS 6736-85-2|Catalposide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Catalposide |
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| CAS Number | 6736-85-2 | Molecular Weight | 482.435 |
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| Density | 1.7±0.1 g/cm3 | Boiling Point | 766.3±60.0 °C at 760 mmHg |
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| Molecular Formula | C22H26O12 | Melting Point | 215-216.5° |
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| MSDS | ChineseUSA | Flash Point | 266.7±26.4 °C |
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Names
| Name | catalpin |
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| Synonym | More Synonyms |
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Catalposide BiologicalActivity
| Description | Catalposide, an iridoid glycoside that could be isolated from Catalpa ovate G. Don (Bignoniaceae), inhibits TNF-α, IL-1β, and IL-6 productions and NF-κB (p65) activation in lipopolysaccharide-activated RAW 264.7 macrophages[1]. |
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| Related Catalog | Research Areas >>Inflammation/Immunology |
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| In Vitro | Catalposide (1-1000 ng/mL) could inhibit TNF-a, IL-1β, and IL-6 productions in RAW 264.7 macrophages[1]. |
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| References | [1]. S J An, et al. Inhibition of TNF-alpha, IL-1beta, and IL-6 productions and NF-kappa B activation in lipopolysaccharide-activated RAW 264.7 macrophages by catalposide, an iridoid glycoside isolated from Catalpa ovata G. Don (Bignoniaceae). Int Immunopharmacol. 2002 Jul;2(8):1173-81. |
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Chemical & Physical Properties
| Density | 1.7±0.1 g/cm3 |
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| Boiling Point | 766.3±60.0 °C at 760 mmHg |
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| Melting Point | 215-216.5° |
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| Molecular Formula | C22H26O12 |
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| Molecular Weight | 482.435 |
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| Flash Point | 266.7±26.4 °C |
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| Exact Mass | 482.142426 |
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| PSA | 187.90000 |
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| LogP | -2.18 |
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| Vapour Pressure | 0.0±2.7 mmHg at 25°C |
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| Index of Refraction | 1.696 |
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| InChIKey | UXSACQOOWZMGSE-UHFFFAOYSA-N |
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| SMILES | O=C(OC1C2C=COC(OC3OC(CO)C(O)C(O)C3O)C2C2(CO)OC12)c1ccc(O)cc1 |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- LZ5776783
- CHEMICAL NAME :
- beta-D-Glucopyranoside, 1a,1b,2,5a,6,6a-hexahydro-6-((4-hydroxybenzoyl)oxy)- 1a-(hydroxymethyl)oxireno(4,5)cyclopenta(1,2-c)pyran- 2-yl, (1aS-(1a-alpha,1b-beta,2-beta,5a- beta,6-beta,6a-alpha))-
- CAS REGISTRY NUMBER :
- 6736-85-2
- LAST UPDATED :
- 199806
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C22-H26-O12
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 64,93,1968
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 64,93,1968
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Safety Information
| Hazard Codes | Xi |
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| RIDADR | NONH for all modes of transport |
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| HS Code | 29389090 |
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Articles8
More Articles
| Electrochemical and spectrometric study of antioxidant activity of pomiferin, isopomiferin, osajin and catalposide. J. Pharm. Biomed. Anal. 48(1) , 127-33, (2008) The antioxidant properties of pomiferin, isopomiferin, osajin and catalposide are evaluated. The electrochemical behaviour of these compounds at a carbon paste electrode was studied using square wave ... | |
| Hostplant suitability and defensive chemistry of the Catalpa sphinx, Ceratomia catalpae. J. Chem. Ecol. 29(10) , 2359-67, (2003) The growth and survival of the Catalpa sphinx, Ceratomia catalpae (Sphingidae), were measured on five different species of Catalpa: C. bignonioides, C. bungeii, C. fargeseii, C. ovata, and C. speciosa... | |
| Inhibition of TNF-alpha, IL-1beta, and IL-6 productions and NF-kappa B activation in lipopolysaccharide-activated RAW 264.7 macrophages by catalposide, an iridoid glycoside isolated from Catalpa ovata G. Don (Bignoniaceae). Int. Immunopharmacol. 2(8) , 1173-81, (2002) Catalposide, the major iridoid glycoside isolated from the stem bark of Catalpa ovata G. Don (Bignoniaceae), was found to inhibit the productions of tumor necrosis factor-alpha (TNF-alpha), interleuki... | |
Synonyms
| (1aS,1bS,2S,5aR,6S,6aS)-2-(β-D-Glucopyranosyloxy)-1a-(hydroxymethyl)-1a,1b,2,5a,6,6a-hexahydrooxireno[4,5]cyclopenta[1,2-c]pyran-6-yl 4-hydroxybenzoate |
| [1aS-(1aa,1bb,2b,5ab,6b,6aa)]-1a,1b,2,5a,6,6a-Hexahydro-6-[(4-hydroxybenzoyl)oxy]-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl-b-D-glucopyranoside |
| Einecs 229-789-1 |
| hydroxybenzoylcatalpol |
| Benzoic acid, 4-hydroxy-, (1aS,1bS,2S,5aR,6S,6aS)-2-(β-D-glucopyranosyloxy)-1a,1b,2,5a,6,6a-hexahydro-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-6-yl ester |
| CATALPOSIDE |
