CAS 51644-96-3|N-Boc-1,5-diaminopentane
Introduction：Basic information about CAS 51644-96-3|N-Boc-1,5-diaminopentane, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | N-Boc-1,5-diaminopentane | ||
|---|---|---|---|
| CAS Number | 51644-96-3 | Molecular Weight | 202.294 |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 309.2±25.0 °C at 760 mmHg |
| Molecular Formula | C10H22N2O2 | Melting Point | / |
| MSDS | ChineseUSA | Flash Point | 140.8±23.2 °C |
| Symbol | GHS05 | Signal Word | Danger |
Names
| Name | N-(5-Aminoamyl)Carbamic Acid Tert-Butyl Ester |
|---|---|
| Synonym | More Synonyms |
N-Boc-1,5-diaminopentane BiologicalActivity
| Description | PROTAC Linker 23 is a PROTAC linker, which refers to the alkyl chain composition. PROTAC Linker 23 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
|---|---|
| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
| Target | Alkyl-Chain |
| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. |
Chemical & Physical Properties
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 309.2±25.0 °C at 760 mmHg |
| Molecular Formula | C10H22N2O2 |
| Molecular Weight | 202.294 |
| Flash Point | 140.8±23.2 °C |
| Exact Mass | 202.168121 |
| PSA | 64.35000 |
| LogP | 1.29 |
| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
| Index of Refraction | 1.458 |
| InChIKey | DPLOGSUBQDREOU-UHFFFAOYSA-N |
| SMILES | CC(C)(C)OC(=O)NCCCCCN |
| Storage condition | 2-8°C |
Safety Information
| Symbol | GHS05 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H314 |
| Precautionary Statements | P280-P305 + P351 + P338-P310 |
| Personal Protective Equipment | Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | C: Corrosive; |
| Risk Phrases | R34 |
| Safety Phrases | S26-S36/37/39-S45 |
| RIDADR | UN 2735 8/PG 3 |
| WGK Germany | 3 |
| HS Code | 2924199090 |
Customs
| HS Code | 2924199090 |
|---|---|
| Summary | 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
Articles3
More Articles| Structure-activity relationships among methoctramine-related polymethylene tetraamines. Chain-length and substituent effects on M-2 muscarinic receptor blocking activity. J. Med. Chem. 32 , 79, (1989) Several polymethylene tetraamines related to methoctramine (1) were prepared and evaluated for their blocking activity on M-2 muscarinic receptors in guinea pig atria and ileum. It turned out that ant... | |
| T. Teshima et al. Tetrahedron 47 , 3305, (1991) | |
| V.J. Jasys et al. J. Org. Chem. 57 , 1814, (1992) |
Synonyms
| N-Boc-cadaverine |
| N-(5-Aminopentyl)carbamic Acid tert-Butyl Ester |
| tert-Butyl (5-aminopentyl)carbamate |
| N-(tert-Butoxycarbonyl)-1,5-pentanediamine |
| N-Boc-1,5-diaminopentane |
| tert-butyl N-(5-aminopentyl)carbamate |
| N-Boc-1,5-pentanediamine |
| 2-Methyl-2-propanyl (5-aminopentyl)carbamate |
| Carbamic acid, N-(5-aminopentyl)-, 1,1-dimethylethyl ester |
| N-(5-Aminoamyl)carbamic Acid tert-Butyl Ester |
| MFCD00210020 |
| N-(tert-Butoxycarbonyl)-1,5-diaminopentane |
