CAS 70-78-0|3-Iodo-L-tyrosine
| Common Name | 3-Iodo-L-tyrosine | ||
|---|---|---|---|
| CAS Number | 70-78-0 | Molecular Weight | 307.085 |
| Density | 1.9±0.1 g/cm3 | Boiling Point | 391.0±42.0 °C at 760 mmHg |
| Molecular Formula | C9H10INO3 | Melting Point | 210 °C (dec.)(lit.) |
| MSDS | USA | Flash Point | 190.3±27.9 °C |
Names
| Name | 3-iodo-L-tyrosine |
|---|---|
| Synonym | More Synonyms |
3-Iodo-L-tyrosine BiologicalActivity
| Description | H-Tyr(3-I)-OH is an effective tyrosine hydroxylase inhibitor. |
|---|---|
| Related Catalog | Natural Products >>Acids and AldehydesResearch Areas >>Others |
| Target | Human Endogenous Metabolite |
| In Vitro | H-Tyr(3-I)-OH (3-iodo-L-tyrosine) is as effective inhibitor of tyrosine hydroxylase. At a concentration of 100μM 3-iodo-L-tyrosine inhibits the enzymatic activity 100% and at a concentration of 10μM it inhibits 60-70%[1]. |
| References | [1]. GOLDSTEIN M, et al. INHIBITION OF TYROSINE HYDROXYLASE BY 3-IODO-L-TYROSINE. Life Sci (1962). 1965 Jan;4:261-4. |
Chemical & Physical Properties
| Density | 1.9±0.1 g/cm3 |
|---|---|
| Boiling Point | 391.0±42.0 °C at 760 mmHg |
| Melting Point | 210 °C (dec.)(lit.) |
| Molecular Formula | C9H10INO3 |
| Molecular Weight | 307.085 |
| Flash Point | 190.3±27.9 °C |
| Exact Mass | 306.970520 |
| PSA | 83.55000 |
| LogP | 1.54 |
| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
| Index of Refraction | 1.689 |
| InChIKey | UQTZMGFTRHFAAM-ZETCQYMHSA-N |
| SMILES | NC(Cc1ccc(O)c(I)c1)C(=O)O |
| Storage condition | 2-8°C |
| Water Solubility | dilute aqueous acid: soluble |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Safety Phrases | S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2922509090 |
Customs
| HS Code | 2922509090 |
|---|---|
| Summary | 2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Synonyms
| 3-Iodotyrosine |
| EINECS 200-744-8 |
| 3-IODO-L-TYROSINE |
| MFCD00002608 |
| Monoiodotyrosine |
| 3-Monoiodo-L-tyrosine |
| Tyrosine, 3-iodo-, L- |
| Tyrosine, 3-iodo- |
| H-Tyr(3-I)-OH |
