Introduction：Basic information about CAS 54518-92-2|H-Leu-CMK.HCl, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | H-Leu-CMK.HCl |
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| CAS Number | 54518-92-2 | Molecular Weight | 200.10600 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C7H15Cl2NO | Melting Point | / |
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| MSDS | ChineseUSA | Flash Point | / |
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Names
| Name | (S)-3-Amino-1-chloro-5-methylhexan-2-one hydrochloride |
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| Synonym | More Synonyms |
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H-Leu-CMK.HCl BiologicalActivity
| Description | (S)-3-Amino-1-chloro-5-methylhexan-2-one hydrochloride is a leucine derivative[1]. |
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| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
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| In Vitro | Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1]. |
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| References | [1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144. |
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Chemical & Physical Properties
| Molecular Formula | C7H15Cl2NO |
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| Molecular Weight | 200.10600 |
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| Exact Mass | 199.05300 |
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| PSA | 43.09000 |
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| LogP | 2.67000 |
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| InChIKey | DRZZRBOLWKRHPF-RGMNGODLSA-N |
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| SMILES | CC(C)CC(N)C(=O)CCl.Cl |
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Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| RIDADR | NONH for all modes of transport |
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| WGK Germany | 3.0 |
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| HS Code | 2922399090 |
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Customs
| HS Code | 2922399090 |
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| Summary | 2922399090 other amino-aldehydes, amino-ketones and amino-quinones, other than those containing more than one kind of oxygen function; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |
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Articles6
More Articles
| Acylpeptide hydrolase: inhibitors and some active site residues of the human enzyme. J. Biol. Chem. 267 , 3811-3818, (1992) Acylpeptide hydrolase may be involved in N-terminal deacetylation of nascent polypeptide chains and of bioactive peptides. The activity of this enzyme from human erythrocytes is sensitive to anions su... | |
| Acetylleucine chloromethyl ketone, an inhibitor of acylpeptide hydrolase, induces apoptosis of U937 cells. Biochem. Biophys. Res. Commun. 263 , 139-142, (1999) Acetylleucine chloromethyl ketone (ALCK), an inhibitor of acylpeptide hydrolase (ACPH), inhibited the growth of human monoblastic U937 cells in a dose- and time-dependent manner. Morphology of the ALC... | |
| Chloromethyl ketones are insulin-like stimulators of lipid synthesis in locust fat body. Arch. Insect Biochem. Physiol. 39 , 9-17, (1998) N alpha-tosyl-L-lysine chloromethyl ketone (TLCK) stimulates lipid synthesis in locust fat body in vitro, and is able to reverse the inhibitory effects of AKH-I on lipid synthesis. Effective stimulato... | |
Synonyms
| l-leucine chloromethyl ketone hydrochloride |
| MFCD00238011 |
