Introduction:Basic information about CAS 115-51-5|Ambutonium bromide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Ambutonium bromide |
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| CAS Number | 115-51-5 | Molecular Weight | 391.34500 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C20H27BrN2O | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 3-carbamoyl-3,3-diphenylpropyl(ethyl)dimethylammonium bromide |
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| Synonym | More Synonyms |
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Ambutonium bromide BiologicalActivity
| Description | Ambutonium bromide is an acetylcholine antagonist. |
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| Related Catalog | Signaling Pathways >>GPCR/G Protein >>mAChRSignaling Pathways >>Neuronal Signaling >>mAChRResearch Areas >>Inflammation/Immunology |
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| Target | Acetylcholine[1] |
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| In Vitro | Ambutonium bromide is a new anticholinergic agent in ulcer therapy[2]. |
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| References | [1]. Southgate PJ. Central and peripheral actions of the acetylcholine antagonist, ambutonium bromide. Arch Int Pharmacodyn Ther. 1972 Apr;196(2):376-82. [2]. SCHWARTZ IR, et al. The effect of ambutonium bromide, a new anticholinergic agent in ulcer therapy. Am J Gastroenterol. 1960 Jun;33:704-17. |
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Chemical & Physical Properties
| Molecular Formula | C20H27BrN2O |
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| Molecular Weight | 391.34500 |
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| Exact Mass | 390.13100 |
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| PSA | 43.09000 |
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| LogP | 0.64870 |
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| InChIKey | VTAGVKVPFBOVRM-UHFFFAOYSA-N |
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| SMILES | CC[N+](C)(C)CCC(C(N)=O)(c1ccccc1)c1ccccc1.[Br-] |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- BP0694200
- CHEMICAL NAME :
- Ammonium, (3-carbamoyl-3,3-diphenylpropyl)dimethylethyl-, bromide
- CAS REGISTRY NUMBER :
- 115-51-5
- LAST UPDATED :
- 199404
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C20-H27-N2-O.Br
- MOLECULAR WEIGHT :
- 391.40
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 24302 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 103,100,1955 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83153 No. of Facilities: 805 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 805 (estimated)
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Synonyms
| BL-700 |
| (4-amino-4-oxo-3,3-diphenylbutyl)-ethyl-dimethylazanium bromide |
| BL-700B |
| (4-azanyl-4-oxo-3,3-diphenyl-butyl)-ethyl-dimethyl-azanium bromide |
| ambutonium bromide |
| ethyl-(3-carbamoyl-3,3-diphenyl-propyl)-dimethyl-ammonium,bromide |
| Ambutonium |
| EINECS 204-093-0 |
| Aethyl-(3-carbamoyl-3,3-diphenyl-propyl)-dimethyl-ammonium,Bromid |
| (4-amino-4-keto-3,3-diphenyl-butyl)-ethyl-dimethyl-ammonium bromide |
| R-100 |