Introduction：Basic information about CAS 123940-54-5|Hypocrellin B, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Hypocrellin B |
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| CAS Number | 123940-54-5 | Molecular Weight | 528.506 |
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| Density | 1.5±0.1 g/cm3 | Boiling Point | 893.8±65.0 °C at 760 mmHg |
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| Molecular Formula | C30H24O9 | Melting Point | 261-263℃ |
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| MSDS | / | Flash Point | 301.4±27.8 °C |
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Names
| Name | 1H-Cyclohepta(ghi)perylene-5,12-dione, 3-acetyl-6,11-dihydroxy-4,8,9,13-tetramethoxy-2-methyl |
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| Synonym | More Synonyms |
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Hypocrellin B BiologicalActivity
| Description | Hypocrellin B, a pigment isolated from the fungi Hypocrella bambusae and Shiraia bambusicola, is an apoptosis inducer. Hypocrellin B can be used as a photosensitizer for photodynamic therapy of cancer. Hypocrellin B also has antimicrobial and antileishmanial activities[1][2][3]. |
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| Related Catalog | Signaling Pathways >>Apoptosis >>ApoptosisResearch Areas >>CancerResearch Areas >>Infection |
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| References | [1]. Miller GG, et al. Preclinical assessment of hypocrellin B and hypocrellin B derivatives as sensitizers for photodynamic therapy of cancer: progress update. Photochem Photobiol. 1997 Apr;65(4):714-22. [2]. Wang X, et al. Hypocrellin B-mediated sonodynamic action induces apoptosis of hepatocellular carcinoma cells. Ultrasonics. 2012 Apr;52(4):543-6. [3]. Ma G, et al. Antimicrobial and antileishmanial activities of hypocrellins A and B. Antimicrob Agents Chemother. 2004 Nov;48(11):4450-2. |
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Chemical & Physical Properties
| Density | 1.5±0.1 g/cm3 |
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| Boiling Point | 893.8±65.0 °C at 760 mmHg |
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| Melting Point | 261-263℃ |
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| Molecular Formula | C30H24O9 |
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| Molecular Weight | 528.506 |
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| Flash Point | 301.4±27.8 °C |
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| Exact Mass | 528.142029 |
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| PSA | 128.59000 |
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| LogP | 5.57 |
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| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
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| Index of Refraction | 1.733 |
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| InChIKey | SBMXTMAIKRQSQE-UHFFFAOYSA-N |
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| SMILES | COc1c(O)c2c(=O)cc(OC)c3c4c(OC)cc(=O)c5c(O)c(OC)c6c(c(c1CC(C)=C6C(C)=O)c23)c54 |
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Synonyms
| 1H-Cyclohepta(ghi)perylene-5,12-dione, 3-acetyl-6,11-dihydroxy-4,8,9,13-tetramethoxy-2-methyl- |
| 3-Acetyl-6,11-dihydroxy-4,8,9,13-tetramethoxy-2-methyl-1H-cyclohepta[ghi]perylene-5,12-dione |
| 1H-Cyclohepta[ghi]perylene-5,12-dione, 3-acetyl-6,11-dihydroxy-4,8,9,13-tetramethoxy-2-methyl- |
| Hypocrellin B |
