CAS 142356-33-0|tert-Butyl (6-bromohexyl)carbamate
Introduction:Basic information about CAS 142356-33-0|tert-Butyl (6-bromohexyl)carbamate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | tert-Butyl (6-bromohexyl)carbamate | ||
|---|---|---|---|
| CAS Number | 142356-33-0 | Molecular Weight | 280.202 |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 340.1±25.0 °C at 760 mmHg |
| Molecular Formula | C11H22BrNO2 | Melting Point | / |
| MSDS | ChineseUSA | Flash Point | 159.5±23.2 °C |
| Symbol | GHS05 | Signal Word | Danger |
Names
| Name | tert-Butyl (6-bromohexyl)carbamate |
|---|---|
| Synonym | More Synonyms |
tert-Butyl (6-bromohexyl)carbamate BiologicalActivity
| Description | Boc-NH-C6-Br is a cleavable linker used for antibody-drug conjugates (ADC)[1]. |
|---|---|
| Related Catalog | Research Areas >>Cancer |
| References | [1]. Jan Anderl, et al. Amatoxin-antibody conjugates. WO2016142049A1. |
Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 340.1±25.0 °C at 760 mmHg |
| Molecular Formula | C11H22BrNO2 |
| Molecular Weight | 280.202 |
| Flash Point | 159.5±23.2 °C |
| Exact Mass | 279.083374 |
| PSA | 38.33000 |
| LogP | 3.63 |
| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
| Index of Refraction | 1.473 |
| InChIKey | NXQXVXILNVTMNA-UHFFFAOYSA-N |
| SMILES | CC(C)(C)OC(=O)NCCCCCCBr |
| Storage condition | 2-8°C |
Safety Information
| Symbol | GHS05 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H318 |
| Precautionary Statements | P280-P305 + P351 + P338 |
| Personal Protective Equipment | Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | Xi |
| Risk Phrases | R41 |
| Safety Phrases | 26-39 |
| RIDADR | UN 3082 9/PG 3 |
| WGK Germany | 3 |
| HS Code | 2924199090 |
Customs
| HS Code | 2924199090 |
|---|---|
| Summary | 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
Articles3
More Articles| Methoxy poly (ethylene glycol)-block-poly (glutamic acid)-graft-6-(2-nitroimidazole) hexyl amine nanoparticles for potential hypoxia-responsive delivery of doxorubicin. J. Biomater. Sci. Polym. Ed. 27 , 40-54, (2015) Tumor microenvironment-responsive nano drug delivery vehicles are gaining mounting attention in the field of biomedical sciences. The hypoxic response of the tumorous cells due to very low partial pre... | |
| T.H. Keller, R. Haener Helv. Chim. Acta 76 , 884, (1993) | |
| D. Damour et al. Bioorg. Med. Chem. Lett. 6 , 1667 , (1996) |
Synonyms
| tert-butyl N-(6-bromohexyl)carbamate |
| 2-Methyl-2-propanyl (6-bromohexyl)carbamate |
| tert-Butyl (6-bromohexyl)carbamate |
| Carbamic acid, N-(6-bromohexyl)-, 1,1-dimethylethyl ester |
